Cytogenetics
FISH MDM2 12q15 Gene Amplification Test
The FISH MDM2 12q15 Gene Amplification Test uses Fluorescence In Situ Hybridization (FISH) to detect amplification of the MDM2 gene on chromosome 12q15, which is associated with certain cancers. This test aids oncologists in diagnosis and treatment planning.
General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.
Review status: No completed medical review is recorded for this page.
At a glance
Plan your test
- Sample
- Formalin-fixed paraffin-embedded (FFPE) tissue block containing at least 10% tumor tissue.
- Results
- Confirm with the laboratory before booking.
- Preparation
- No patient preparation is required. Ensure the tissue block is properly labeled and accompanied by a completed Chromosome & FISH Analysis Requisition Form (Form 17).
Payment: M-Pesa and card options can be confirmed during booking.
Insurance & government schemes
Is this test covered for you?
We help you verify whether the FISH MDM2 12q15 Gene Amplification Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.
Providers & schemes we can help you check
Government & public schemes
Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.
Private insurers & employer schemes
Names shown for identification only — listing does not imply partnership or guarantee of coverage.
Have these ready when we check
- Insurer or scheme name & policy / member number
- A clinician's request / prescription for the test
- Pre-authorisation letter, if your plan requires one
Free coverage check
Ask us to verify your cover
Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.
Start with fit
Is this the right test for you?
The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.
- ✓Diagnosis of certain cancers, particularly soft tissue sarcomas.
- ✓Prognosis assessment in specific cancer types.
- ✓Guiding treatment decisions for cancers associated with MDM2 amplification.
- ✓Patients with suspected cancer based on clinical presentation.
- ✓Patients with a family history of relevant cancers.
In plain language
What this test helps you understand
This test specifically looks for an increase in the number of copies of the MDM2 gene (amplification). This genetic alteration is found in some types of cancer, including certain soft tissue sarcomas and breast cancers. Understanding if this amplification is present can help healthcare providers assess the potential aggressiveness of a tumor and guide treatment strategies.
Patients experiencing cancer symptoms, those with a family history of cancer, or individuals identified as high-risk by their doctor may be recommended for this test. Discuss with your physician if this test is appropriate for your situation.
Benefits of this test include aiding in the early detection of specific genetic alterations associated with cancer, supporting informed decisions about treatment options, and potentially contributing to personalized treatment plans. Results help oncologists understand the tumor's characteristics and monitor treatment response.
Results will indicate whether MDM2 gene amplification is detected. Discuss the results thoroughly with your oncologist to understand their implications for your specific condition and next steps.
Medical review status
Clinical review pending
A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.
Meet the DNA Labs Kenya medical team →A simple process
What happens next?
You do not have to navigate the test alone. We help you move from question to next step.
Speak with us
We check the test and answer your questions before collection.
Give your sample
Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.
Understand your report
A counselor helps you understand the result and the next steps.
Choose your collection
Home collection or a lab visit
We will explain the sample, preparation, and next steps before anything is collected.
Home collection
Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.
Lab or hub visit
Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.
Ask about locations →Read your report
What common result terms mean
Questions people ask
Frequently asked questions
Collaboration
Open for partnership with hospitals, clinics, doctors & researchers
Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.
Hospitals & clinics
Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.
Doctors & specialists
LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.
Research institutions
Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.
Students & academic projects
Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.
Trust & transparency
Sources, standards & how this page is maintained
Standards & references
- ACMG/AMP technical standards for sequence variant interpretation
- ClinGen curation and gene–disease validity frameworks where applicable
- LOINC-coded reporting for interoperable results
- ISO 9001:2015 quality management; ISO 15189 accreditation in progress
Page provenance
- Last updated: September 27, 2026
- Medical review: not yet completed
- Written for patients & clinicians in Kenya; reviewed periodically against current guidance
Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.
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