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Cytogenetics

FISH Synovial Sarcoma SS18 SYT 18q112 Gene Rearrangement Test

This test detects specific genetic changes (SS18-SYT rearrangement) linked to synovial sarcoma, a rare cancer. It helps confirm diagnosis and guide treatment.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Formalin-fixed paraffin-embedded (FFPE) tissue block containing at least 10% tumor tissue.
Results
Results are typically available within four working days. Confirm with the laboratory before booking.
Preparation
No specific patient preparation is required. The sample is typically obtained via biopsy.
Test priceKSh 24,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the FISH Synovial Sarcoma SS18 SYT 18q112 Gene Rearrangement Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Suspicion of synovial sarcoma based on clinical presentation or biopsy results.
  • ✓Diagnosis of a soft tissue mass near a joint.
  • ✓Need for precise tumor classification to guide treatment.
  • ✓Patients presenting with swelling, pain, or limited mobility near a joint.
02

In plain language

What this test helps you understand

This test helps confirm the diagnosis of synovial sarcoma by detecting the characteristic SS18-SYT gene rearrangement. Accurate diagnosis is crucial for determining the correct treatment plan and prognosis.
The FISH Synovial Sarcoma SS18 SYT 18q112 Gene Rearrangement Test is a specialized diagnostic tool used to identify genetic alterations associated with synovial sarcoma. This is a rare type of cancer that often develops in the soft tissues near joints. The test uses Fluorescence In Situ Hybridization (FISH) technology to look for a specific rearrangement involving the SS18 and SYT genes on chromosome 18. Identifying this rearrangement is important for confirming a diagnosis of synovial sarcoma and helping doctors plan the most appropriate treatment strategy. This test is typically used when a tumor is suspected to be synovial sarcoma based on its appearance under a microscope or other clinical findings.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo specific patient preparation is required. The sample is typically obtained via biopsy.
SampleFormalin-fixed paraffin-embedded (FFPE) tissue block containing at least 10% tumor tissue.
MethodologyFluorescence In Situ Hybridization (FISH). This technique uses fluorescent probes that bind to specific DNA sequences on chromosomes, allowing visualization of gene rearrangements under a microscope.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test detects only the specific SS18-SYT rearrangement. Other genetic alterations may be present. The quality of the tissue sample can affect test results. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Synovial sarcoma is a rare type of cancer that usually develops in the soft tissues around joints, particularly in the arms or legs. It is not related to the synovial membrane itself.
This test detects a specific genetic change called a rearrangement between the SS18 and SYT genes, which is a hallmark of synovial sarcoma.
The test requires a sample of tumor tissue, usually obtained through a biopsy and preserved in formalin, then embedded in paraffin wax (FFPE block).
Results are typically available within four working days, but this can vary. Confirm with the laboratory before booking.
A positive result indicates the presence of the SS18-SYT rearrangement, supporting a diagnosis of synovial sarcoma. A negative result means this specific rearrangement was not detected. Your doctor will interpret the results in the context of your overall health.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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