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Medical information Clinical review pending

Endocrine Testing

Cortisol Stimulation by ACTH Test

The Cortisol Stimulation by ACTH Test evaluates adrenal gland function by measuring cortisol response to synthetic ACTH. It helps diagnose conditions like Cushing's syndrome or adrenal insufficiency.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
2 mL (0.5 mL minimum) serum from 1 Serum Separator Tube (SST) for each timed specimen. Three tubes are required: baseline, 30 minutes post-ACTH, and 60 minutes post-ACTH.
Results
Daily. Confirm with the laboratory before booking.
Preparation
Overnight fasting is required before the test. Synthetic ACTH (Synacthen) is not supplied by the laboratory; it must be obtained separately by the ordering physician or facility.
Test priceKSh 3,861

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Cortisol Stimulation by ACTH Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Suspected adrenal insufficiency
  • ✓Suspected Cushing's syndrome
  • ✓Evaluation of unexplained fatigue or weight changes
  • ✓Monitoring adrenal function
  • ✓Assessment of pituitary-adrenal axis function
  • ✓Diagnosis of congenital adrenal hyperplasia
02

In plain language

What this test helps you understand

This test is used to diagnose adrenal disorders, including adrenal insufficiency (Addison's disease) and Cushing's syndrome. It assesses the adrenal glands' ability to respond to ACTH stimulation, which is crucial for regulating cortisol production.
The Cortisol Stimulation by ACTH Test is a diagnostic procedure used to assess how well your adrenal glands are working. Your adrenal glands produce cortisol, a hormone essential for many bodily functions. This test involves measuring your cortisol levels in the blood before and after you receive an injection of synthetic ACTH (Adrenocorticotropic Hormone), a substance that normally stimulates your adrenal glands to produce cortisol.

This test helps doctors understand if your adrenal glands are producing too much or too little cortisol. It is a key tool in diagnosing conditions related to adrenal function, such as Cushing's syndrome (excess cortisol) or adrenal insufficiency (insufficient cortisol).

If you are experiencing symptoms like unexplained fatigue, significant weight changes, mood disturbances, or skin changes, this test might be recommended by your doctor. It can also be useful for individuals with a family history of endocrine disorders. Understanding your adrenal function is important for effective diagnosis and treatment.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationOvernight fasting is required before the test. Synthetic ACTH (Synacthen) is not supplied by the laboratory; it must be obtained separately by the ordering physician or facility.
Sample2 mL (0.5 mL minimum) serum from 1 Serum Separator Tube (SST) for each timed specimen. Three tubes are required: baseline, 30 minutes post-ACTH, and 60 minutes post-ACTH.
MethodologyThis test involves measuring cortisol levels in serum samples using laboratory techniques. Samples are collected at baseline, 30 minutes, and 60 minutes after intravenous administration of synthetic ACTH.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
The test requires accurate timing of blood draws and administration of ACTH. Certain medications can interfere with test results. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

This test helps diagnose conditions related to adrenal gland function, such as adrenal insufficiency (too little cortisol) or Cushing's syndrome (too much cortisol).
Yes, overnight fasting is required before the test.
The test involves blood draws at three different times: baseline, 30 minutes after ACTH administration, and 60 minutes after ACTH administration. The procedure itself is relatively quick, but the total time commitment is about 1 hour.
No, synthetic ACTH (Synacthen) is not supplied by the laboratory. It must be obtained separately.
Your doctor will receive the results and interpret them based on your medical history and symptoms. They will discuss the findings with you and recommend any necessary follow-up steps.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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