Medical information Clinical review pending

Genetic Testing

Best1 Gene Bestrophinopathy Genetic Test

The Best1 Gene Bestrophinopathy NGS Genetic DNA Test identifies mutations in the BEST1 gene linked to Bestrophinopathy, a genetic vision disorder. Utilizes Next-Generation Sequencing (NGS) for comprehensive analysis.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
Results: Approximately 3 to 4 weeks. Confirm with the laboratory before booking.
Preparation: A clinical history of the patient is required. A genetic counseling session to create a pedigree chart of affected family members is recommended prior to testing. Confirm with the laboratory before booking.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Best1 Gene Bestrophinopathy Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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+254

Insurer or scheme

Policy / member number (optional)

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Individuals experiencing unexplained vision loss.
✓Patients with symptoms suggestive of Bestrophinopathy (e.g., changes in color perception, difficulty seeing in low light).
✓Individuals with a family history of Bestrophinopathy or related retinal disorders.
✓Diagnosis confirmation for suspected Bestrophinopathy.
✓Genetic counseling for affected families.

In plain language

What this test helps you understand

This test helps identify mutations in the BEST1 gene, which are associated with Bestrophinopathy, a genetic disorder affecting vision. It aids in confirming a diagnosis, understanding the underlying cause of visual impairment, and guiding management strategies.

The Best1 Gene Bestrophinopathy NGS Genetic DNA Test is a diagnostic tool used to identify mutations in the BEST1 gene. This gene is associated with Bestrophinopathy, a genetic condition that can affect vision. The test uses Next-Generation Sequencing (NGS) technology to provide a detailed analysis of the BEST1 gene, helping to detect abnormalities that may cause ocular problems. Understanding the genetic basis of vision disorders is important for early diagnosis and management. This test can help confirm a diagnosis and guide treatment decisions. The test specifically examines the BEST1 gene, which is important for retinal health. Identifying mutations can help healthcare providers understand the cause of visual impairment. Individuals experiencing vision loss, changes in color perception, or difficulty seeing in low light may benefit from this test. It is also recommended for those with a family history of Bestrophinopathy or related eye conditions. Taking this test allows for early detection of genetic vision conditions, informed treatment decisions, potential family planning guidance, and access to targeted therapies. Results will indicate the presence of mutations in the BEST1 gene. A healthcare provider or genetic counselor will help interpret the results and discuss their implications.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationA clinical history of the patient is required. A genetic counseling session to create a pedigree chart of affected family members is recommended prior to testing. Confirm with the laboratory before booking.

SampleBlood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.

MethodologyNext-Generation Sequencing (NGS) is used to analyze the BEST1 gene.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test analyzes the BEST1 gene specifically. It may not detect mutations in other genes that can cause similar symptoms. Confirm with the laboratory before booking.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

Bestrophinopathy is a genetic disorder that affects the retina, potentially leading to vision loss. It is caused by mutations in the BEST1 gene.

Individuals experiencing symptoms like vision loss, changes in color perception, or difficulty seeing in low light, especially with a family history of similar conditions, should consider this test.

The test involves analyzing a sample of your blood or DNA using Next-Generation Sequencing (NGS) to look for mutations in the BEST1 gene.

A healthcare provider or genetic counselor will explain the test results, including whether any mutations in the BEST1 gene were found and what they might mean for your health.

A genetic counseling session is recommended prior to testing to discuss family history and the implications of the test. Confirm with the laboratory before booking.

The turnaround time is typically 3 to 4 weeks. Confirm with the laboratory before booking.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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