Medical information Clinical review pending

Genetic Testing

CDKL5 Gene Angelmanlike Syndrome Genetic Test

Genetic test using Next Generation Sequencing (NGS) to detect mutations in the CDKL5 gene, associated with Angelman-like syndrome and other neurological disorders. Helps diagnose conditions causing developmental delays, speech impairments, and motor dysfunction.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube) or Saliva sample (collection kit provided). Confirm specific requirements with the laboratory before booking.
Results: Results are typically available within 3 to 4 weeks. Confirm with the laboratory before booking.
Preparation: No special preparation is typically required for this test. Confirm with the laboratory before booking.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the CDKL5 Gene Angelmanlike Syndrome Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Mobile number *

+254

Insurer or scheme

Policy / member number (optional)

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Severe developmental delays
✓Speech impairments
✓Motor function challenges
✓Seizures
✓Family history of neurological disorders
✓Suspected Angelman-like syndrome

In plain language

What this test helps you understand

This test helps identify mutations in the CDKL5 gene, which are linked to Angelman-like syndrome and other severe neurological disorders. Identifying a mutation can confirm a diagnosis, guide management strategies, and provide information for genetic counseling and family planning.

The CDKL5 Gene Angelmanlike Syndrome NGS Genetic DNA Test is a specialized genetic analysis used to identify mutations within the CDKL5 gene. This gene plays a crucial role in brain development, and mutations can lead to severe neurological conditions, often presenting similarly to Angelman syndrome. This test employs advanced Next Generation Sequencing (NGS) technology to provide a detailed examination of the CDKL5 gene. It is designed to help diagnose the underlying genetic cause of developmental and cognitive disabilities. Understanding the specific genetic mutation can aid in prognosis, management, and family planning. Genetic counseling is recommended before testing to discuss the potential implications and family history.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationNo special preparation is typically required for this test. Confirm with the laboratory before booking.

SampleBlood sample (EDTA tube) or Saliva sample (collection kit provided). Confirm specific requirements with the laboratory before booking.

MethodologyNext Generation Sequencing (NGS) analysis of the CDKL5 gene.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test specifically analyzes the CDKL5 gene. It may not detect mutations in other genes that could cause similar symptoms. Results should be interpreted in the context of clinical findings and family history. Confirm with the laboratory before booking.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

Angelman-like syndrome is a severe neurological disorder characterized by developmental delays, speech impairment, movement or balance disorders, and often seizures. It shares similarities with Angelman syndrome but is caused by mutations in the CDKL5 gene.

Individuals experiencing severe developmental delays, speech problems, motor difficulties, or seizures, especially if these symptoms suggest Angelman-like syndrome, may be candidates for this test. A family history of similar conditions is also a factor.

The test involves analyzing a sample of your blood or saliva to look for specific changes (mutations) in the CDKL5 gene using Next Generation Sequencing (NGS) technology.

The turnaround time for results is typically 3 to 4 weeks, but this can vary. Confirm the current turnaround time with the laboratory before booking.

Yes, genetic counseling is highly recommended before and after testing. A genetic counselor can help you understand the test, its implications, potential results, and how they might affect you and your family.

Your doctor will discuss the results with you and help interpret them in the context of your clinical picture and family history. This information can guide further management and treatment options.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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