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Medical information Clinical review pending

Genetic Testing

CLDN16 Gene Hypomagnesemia Type 3 Genetic Test

Genetic test to identify mutations in the CLDN16 gene, associated with Hypomagnesemia Type 3, a condition affecting magnesium levels. Helps diagnose the genetic cause of low magnesium.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample, Extracted DNA, or One drop of blood on an FTA Card.
Results
Confirm with the laboratory before booking.
Preparation
Provide clinical history of the patient. A genetic counseling session to draw a pedigree chart of affected family members is recommended.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the CLDN16 Gene Hypomagnesemia Type 3 Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Symptoms suggestive of low magnesium levels (e.g., muscle cramps, fatigue, irregular heartbeat).
  • ✓Family history of hypomagnesemia or related metabolic disorders.
  • ✓Diagnosis confirmation for suspected hypomagnesemia type 3.
  • ✓Genetic counseling for individuals with low magnesium levels.
02

In plain language

What this test helps you understand

This test helps identify the genetic cause of hypomagnesemia type 3, enabling targeted management strategies and providing insights into family health risks.
The CLDN16 Gene Hypomagnesemia Type 3 NGS Genetic DNA Test is a diagnostic tool used to detect genetic mutations linked to hypomagnesemia type 3. This condition impacts how the body manages magnesium levels, potentially leading to various metabolic issues. Understanding your genetic factors is key for effective health management.

This test specifically analyzes genetic variations within the CLDN16 gene. This gene is important for magnesium transport in the body. Identifying variations can help healthcare providers understand the genetic basis of low magnesium levels.

Individuals experiencing symptoms like muscle cramps, fatigue, or irregular heartbeats, which can be associated with low magnesium, might consider this test. It may also be beneficial for those with a family history of hypomagnesemia or related metabolic conditions to assess potential genetic risks.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationProvide clinical history of the patient. A genetic counseling session to draw a pedigree chart of affected family members is recommended.
SampleBlood sample, Extracted DNA, or One drop of blood on an FTA Card.
MethodologyNext Generation Sequencing (NGS) analysis of the CLDN16 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically analyzes the CLDN16 gene. Other genetic or non-genetic factors can cause hypomagnesemia. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Hypomagnesemia Type 3 is a condition characterized by low levels of magnesium in the blood, caused by specific genetic mutations affecting magnesium transport.
Individuals with symptoms of low magnesium or a family history of hypomagnesemia may benefit from this test. Consult your doctor.
The test involves analyzing a sample of your blood or DNA to look for specific changes in the CLDN16 gene.
Results indicate the presence or absence of specific mutations in the CLDN16 gene. A genetic counselor can help interpret the results.
Confirm with the laboratory before booking.
The test price is KSh 40,000. Confirm with the laboratory before booking.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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