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Medical information Clinical review pending

Genetic Testing

COL15A1 Gene Early Onset Glaucoma Phenotype Modifier of COL15A1 Related Genetic Test

This genetic test identifies mutations in the COL15A1 gene associated with early onset glaucoma, helping individuals understand their risk and inform management strategies.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample, extracted DNA, or one drop of blood on an FTA card.
Results
Approximately 3 to 4 weeks. Confirm with the laboratory before booking.
Preparation
Confirm with the laboratory before booking. Generally, no special preparation is required for a blood sample.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the COL15A1 Gene Early Onset Glaucoma Phenotype Modifier of COL15A1 Related Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Family history of early onset glaucoma
  • ✓Personal history of glaucoma
  • ✓Symptoms suggestive of glaucoma (e.g., vision changes, eye pain)
  • ✓Risk assessment for individuals with genetic predisposition
  • ✓Guiding preventative eye care strategies
02

In plain language

What this test helps you understand

Identifies genetic mutations in the COL15A1 gene associated with early onset glaucoma, aiding in risk assessment and management planning.
The COL15A1 Gene Early Onset Glaucoma Test is a specialized genetic analysis focusing on the COL15A1 gene. Mutations in this gene have been linked to an increased risk of developing glaucoma at an earlier age. Glaucoma is a serious eye condition that can lead to irreversible vision loss if not managed effectively. This test provides valuable information for individuals concerned about their risk.

This test specifically looks for genetic variations within the COL15A1 gene. By examining your DNA, the test can identify specific mutations that may contribute to the development of early onset glaucoma. Understanding these genetic factors is important for proactive eye care.

Individuals with a family history of glaucoma, or those experiencing symptoms like increased eye pressure, vision changes, or eye pain, may benefit from this test. Consulting with a healthcare provider is recommended to determine if this genetic evaluation is appropriate.

Understanding your genetic predisposition can empower you and your doctor to make informed decisions about monitoring and potential treatments. Early detection and management are key to preserving vision. Discussing the results with a genetic counselor is often recommended to fully understand the implications.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationConfirm with the laboratory before booking. Generally, no special preparation is required for a blood sample.
SampleBlood sample, extracted DNA, or one drop of blood on an FTA card.
MethodologyNext Generation Sequencing (NGS) genetic DNA test.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test only analyzes the COL15A1 gene. Glaucoma can be influenced by other genes and environmental factors. A negative result does not completely rule out the risk of developing glaucoma. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Early onset glaucoma refers to glaucoma that develops at a younger age than typical, often before age 40. It can be associated with specific genetic mutations.
This test is often recommended for individuals with a family history of glaucoma, especially early onset cases, or those showing symptoms suggestive of the condition.
The test involves analyzing a sample of your DNA (usually from a blood sample) to look for specific mutations in the COL15A1 gene.
Results should be discussed with your healthcare provider or a genetic counselor to understand their meaning in the context of your personal and family medical history.
This test identifies genetic risk factors, but it cannot definitively predict whether someone will develop glaucoma. Other factors also play a role.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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