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Medical information Clinical review pending

Genetic Testing

DNMT3A Gene Acute Myeloid Leukemia Somatic DNMT3A Related Genetic Test

This genetic test identifies mutations in the DNMT3A gene associated with Acute Myeloid Leukemia (AML). It uses Next Generation Sequencing (NGS) to provide insights for diagnosis and treatment planning.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube). Confirm specific requirements with the laboratory before booking.
Results
Confirm with the laboratory before booking.
Preparation
No special preparation is typically required. Confirm with the laboratory before booking.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the DNMT3A Gene Acute Myeloid Leukemia Somatic DNMT3A Related Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Diagnosis of Acute Myeloid Leukemia (AML)
  • ✓Prognosis assessment in AML
  • ✓Guiding treatment decisions in AML
  • ✓Identifying potential targets for therapy
  • ✓Family history of AML or related hematological malignancies
  • ✓Research purposes
02

In plain language

What this test helps you understand

Identifies somatic mutations in the DNMT3A gene associated with Acute Myeloid Leukemia (AML), aiding in diagnosis, prognosis, and treatment planning.
The DNMT3A Gene Acute Myeloid Leukemia Somatic DNMT3A Related NGS Genetic DNA Test is a diagnostic tool used to identify mutations in the DNMT3A gene linked to acute myeloid leukemia (AML). This test utilizes Next Generation Sequencing (NGS) technology for a detailed analysis of genetic material, detecting specific mutations that can influence AML development and progression.

This genetic test measures the presence of somatic mutations in the DNMT3A gene. This gene is important for DNA methylation and gene regulation. Identifying these mutations can provide valuable information about the risk and prognosis of AML.

Individuals diagnosed with acute myeloid leukemia, those with a family history of AML or related blood cancers, or patients experiencing symptoms like persistent fatigue, frequent infections, or easy bruising may be considered for this test.

Taking this test can help doctors tailor treatment plans based on genetic findings, provide information on prognosis, aid in early detection and monitoring, and support genetic counseling for family members.

Results will indicate the presence or absence of mutations. A healthcare provider, such as a genetic counselor or oncologist, will help interpret the results and discuss their implications for treatment and family health.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is typically required. Confirm with the laboratory before booking.
SampleBlood sample (EDTA tube). Confirm specific requirements with the laboratory before booking.
MethodologyNext Generation Sequencing (NGS) of genomic DNA.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test detects specific somatic mutations in the DNMT3A gene. It may not detect all possible mutations or other genetic factors contributing to AML. Results should be interpreted alongside clinical findings.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

The DNMT3A gene provides instructions for making an enzyme involved in regulating gene activity through DNA methylation. Mutations in this gene are associated with certain cancers, including AML.
Acute Myeloid Leukemia (AML) is a type of cancer that affects the blood and bone marrow, characterized by the rapid growth of abnormal white blood cells.
This test is typically recommended for individuals diagnosed with AML, those with a family history of AML, or those with symptoms suggestive of the disease. Your doctor will determine if this test is appropriate for you.
A healthcare professional, such as a genetic counselor or oncologist, will interpret the test results and discuss their meaning in relation to your specific health situation.
Insurance coverage varies. Confirm with your insurance provider and the laboratory regarding coverage and costs.
You can book the test by calling or WhatsApping +254711564616. We offer services in Nairobi, Mombasa, Kisumu, and home sample collection.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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