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Medical information Clinical review pending

Genetic Testing

ERCC5 Gene Xeroderma Pigmentosum Group G Genetic Test

Genetic test for mutations in the ERCC5 gene associated with Xeroderma Pigmentosum Group G, a condition causing extreme sensitivity to UV light and increased skin cancer risk.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (usually collected in an EDTA tube). Confirm specific requirements with the laboratory before booking.
Results
Confirm with the laboratory before booking.
Preparation
No special preparation is typically required for this blood test. However, confirm with the laboratory for any specific instructions.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the ERCC5 Gene Xeroderma Pigmentosum Group G Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Suspected Xeroderma Pigmentosum (XP) based on clinical symptoms.
  • ✓Family history of XP or early-onset skin cancers.
  • ✓Extreme sensitivity to sunlight.
  • ✓Recurrent skin lesions or cancers at a young age.
  • ✓Genetic counseling for individuals with a family history of XP.
  • ✓Confirmation of diagnosis in individuals with compatible clinical features.
02

In plain language

What this test helps you understand

This test helps identify specific genetic mutations in the ERCC5 gene associated with Xeroderma Pigmentosum Group G. Identifying these mutations can confirm a diagnosis, aid in understanding the genetic basis of the condition, and inform management strategies related to UV exposure and skin cancer risk.
The ERCC5 Gene Xeroderma Pigmentosum Group G NGS Genetic DNA Test is an advanced diagnostic tool used to identify genetic changes in the ERCC5 gene. This gene is linked to Xeroderma Pigmentosum (XP) Group G, a rare condition where individuals have a significantly heightened sensitivity to ultraviolet (UV) light from the sun. This sensitivity dramatically increases their risk of developing skin cancers at an early age. The test uses Next-Generation Sequencing (NGS) technology to provide a detailed analysis of the ERCC5 gene. Understanding potential mutations can help individuals and their healthcare providers manage risks associated with XP. This test is important for diagnosis and understanding familial risk.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is typically required for this blood test. However, confirm with the laboratory for any specific instructions.
SampleBlood sample (usually collected in an EDTA tube). Confirm specific requirements with the laboratory before booking.
MethodologyNext-Generation Sequencing (NGS) of the ERCC5 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically analyzes the ERCC5 gene. It does not detect mutations in other genes associated with Xeroderma Pigmentosum or other conditions. A negative result does not completely rule out XP if clinical suspicion remains high. Results may be affected by sample quality.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

XP is a rare genetic disorder characterized by an extreme sensitivity to ultraviolet (UV) light, leading to a very high risk of developing skin cancers.
Mutations in the ERCC5 gene are known to cause Xeroderma Pigmentosum Group G. Testing this gene helps identify the specific genetic cause in individuals suspected of having this condition.
A positive result indicates the presence of a mutation in the ERCC5 gene associated with XP Group G. It's important to discuss this with your doctor to understand the implications for your health and family.
A negative result means no mutations associated with XP Group G were found in the ERCC5 gene. However, it doesn't entirely rule out XP, as other genes can be involved. Discuss the result with your doctor.
Typically, no special preparation is needed. A blood sample will be collected. Confirm any specific instructions with the laboratory beforehand.
Turnaround time varies. Please confirm the expected timeframe with the laboratory before booking your test.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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