Medical information Clinical review pending

Genetic Testing

HSD11B2 Gene Apparent Mineralocorticoid Excess Genetic Test

Genetic test for the HSD11B2 gene to help diagnose conditions like apparent mineralocorticoid excess, which can cause high blood pressure and electrolyte imbalances. Uses Next Generation Sequencing (NGS) technology.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
Results: Confirm with the laboratory before booking. Typically 3 to 4 weeks.
Preparation: Confirm with the laboratory before booking. Patients should provide a detailed clinical history and family medical history. A genetic counseling session may be recommended prior to testing.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the HSD11B2 Gene Apparent Mineralocorticoid Excess Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

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Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Unexplained high blood pressure (hypertension)
✓Low potassium levels (hypokalemia)
✓Muscle weakness or cramping
✓Severe fatigue
✓Family history of apparent mineralocorticoid excess or related metabolic disorders
✓Evaluation of endocrine disorders

In plain language

What this test helps you understand

This test helps identify genetic mutations in the HSD11B2 gene associated with apparent mineralocorticoid excess and related metabolic disorders. It aids in confirming a diagnosis, understanding the underlying cause of symptoms like hypertension and low potassium, and guiding appropriate management strategies.

The HSD11B2 Gene Apparent Mineralocorticoid Excess NGS Genetic DNA Test is a diagnostic tool used to identify genetic changes (mutations) in the HSD11B2 gene. This gene provides instructions for making an enzyme important for regulating cortisol and aldosterone, hormones that affect blood pressure and electrolyte balance. This test uses Next Generation Sequencing (NGS) technology for accurate analysis. Understanding genetic predispositions related to mineralocorticoid metabolism is important for personalized medical care. This test can help identify the cause of certain metabolic disorders and guide treatment decisions. It is particularly relevant for individuals with symptoms suggestive of apparent mineralocorticoid excess or a family history of related conditions.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationConfirm with the laboratory before booking. Patients should provide a detailed clinical history and family medical history. A genetic counseling session may be recommended prior to testing.

SampleBlood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.

MethodologyNext Generation Sequencing (NGS) of the HSD11B2 gene.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test analyzes specific regions of the HSD11B2 gene. It may not detect all possible mutations, such as deep intronic changes or large deletions/duplications, unless specifically requested. Results should be interpreted alongside clinical findings.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

Apparent mineralocorticoid excess is a condition where the body's mineralocorticoid receptors are overstimulated, leading to symptoms like high blood pressure and low potassium, even when mineralocorticoid hormone levels are normal. It can be caused by genetic mutations.

Individuals with unexplained high blood pressure, low potassium levels, muscle weakness, or a family history of similar conditions should discuss this test with their doctor.

A sample can be collected as a blood draw, extracted DNA, or a single drop of blood on a special card (FTA card). Home collection services may be available.

Results are typically available within 3 to 4 weeks, but this can vary. Confirm the exact turnaround time with the laboratory before booking.

Your results will be provided in a report. It is crucial to discuss the findings with your healthcare provider to understand their implications and plan any necessary follow-up steps.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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