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Medical information Clinical review pending

Genetic Testing

IL1RN Gene Osteomyelitis Sterile Multifocal with Periostitis and Pustulosis Genetic Test

Genetic test for the IL1RN gene to assess predisposition to specific forms of osteomyelitis (bone infection) involving inflammation and skin pustules. Uses Next Generation Sequencing (NGS).

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
Results
Approximately 3 to 4 weeks. Confirm with the laboratory before booking.
Preparation
No specific fasting is required. Confirm with the laboratory before booking.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the IL1RN Gene Osteomyelitis Sterile Multifocal with Periostitis and Pustulosis Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Individuals with suspected sterile multifocal osteomyelitis.
  • ✓Patients presenting with bone pain, swelling, fever, and skin pustules.
  • ✓Family history of similar inflammatory bone conditions.
  • ✓Cases where standard infection diagnostics are negative.
  • ✓To understand genetic predisposition to specific inflammatory responses.
02

In plain language

What this test helps you understand

This test helps identify genetic variations in the IL1RN gene that may be associated with a predisposition to sterile multifocal osteomyelitis with periostitis and pustulosis. It can provide insights into the underlying genetic factors contributing to the condition, potentially informing diagnosis and treatment strategies.
The IL1RN Gene Osteomyelitis Sterile Multifocal with Periostitis and Pustulosis NGS Genetic DNA Test examines the IL1RN gene. This gene is involved in regulating inflammation and the immune response. This test is specifically designed to help understand the genetic factors associated with certain types of osteomyelitis, a bone infection characterized by being sterile (not caused by typical bacteria), affecting multiple bone sites (multifocal), and accompanied by inflammation of the bone's outer layer (periostitis) and skin pustules. Understanding genetic predispositions can aid in diagnosis and management. This test utilizes Next Generation Sequencing (NGS) technology for detailed analysis.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo specific fasting is required. Confirm with the laboratory before booking.
SampleBlood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
MethodologyNext Generation Sequencing (NGS) of the IL1RN gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test identifies specific genetic variations in the IL1RN gene. It does not rule out other causes of osteomyelitis or related conditions. A negative result does not guarantee an absence of predisposition. Interpretation requires clinical correlation.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Osteomyelitis is an infection or inflammation of the bone. The type this test focuses on is sterile (not caused by common bacteria), multifocal (affecting multiple bones), and associated with periostitis (inflammation of the bone surface) and pustulosis (skin pustules).
The IL1RN gene provides instructions for making a protein that helps control inflammation. Variations in this gene can affect the body's inflammatory response.
Individuals with symptoms suggestive of sterile multifocal osteomyelitis with periostitis and pustulosis, or those with a family history of similar conditions, may be candidates for this test. Consult your doctor.
Results will indicate the presence or absence of specific genetic variations in the IL1RN gene. A healthcare professional, potentially a genetic counselor, should interpret the results in the context of your clinical picture.
Insurance coverage varies. Please check with your insurance provider regarding coverage for genetic testing.
We have laboratory branches in Nairobi, Mombasa, and Kisumu, and offer home sample collection services. Contact us to book.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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