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Genetic Testing

IRF8 Gene Immunodeficiency Type 32B Monocyte and Dendritic Cell Deficiency Autosomal Recessive Genetic Test

Genetic test for IRF8 gene mutations associated with Immunodeficiency Type 32B, affecting monocyte and dendritic cell function. Helps identify predisposition to immunodeficiency disorders.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube) or extracted DNA. Confirm specific requirements with the laboratory before booking.
Results
Results are typically available within 3 to 4 weeks. Confirm exact turnaround time with the laboratory before booking.
Preparation
No specific patient preparation is required for a blood draw. Discuss any medications or recent illnesses with your doctor.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the IRF8 Gene Immunodeficiency Type 32B Monocyte and Dendritic Cell Deficiency Autosomal Recessive Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Recurrent or severe infections
  • ✓Family history of immunodeficiency disorders
  • ✓Clinical suspicion of primary immunodeficiency
  • ✓Evaluation of monocyte or dendritic cell abnormalities
  • ✓Genetic counseling for families with known IRF8 mutations
02

In plain language

What this test helps you understand

This test identifies mutations in the IRF8 gene associated with Immunodeficiency Type 32B, a rare autosomal recessive disorder characterized by monocyte and dendritic cell deficiency. Identifying these mutations can help confirm a diagnosis, understand disease mechanisms, and guide management strategies for affected individuals.
The IRF8 Gene Immunodeficiency Type 32B test is a genetic examination using Next Generation Sequencing (NGS) to identify specific changes (mutations) in the IRF8 gene. This gene plays a crucial role in the development and function of monocytes and dendritic cells, which are important components of the immune system. Understanding potential variations in this gene can provide valuable insights into susceptibility to certain immunodeficiency disorders. This test is particularly relevant for individuals with a family history of immune system problems or those experiencing recurrent infections. Early detection can lead to better management and informed healthcare decisions. We offer genetic counseling to help assess risks and understand test implications.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo specific patient preparation is required for a blood draw. Discuss any medications or recent illnesses with your doctor.
SampleBlood sample (EDTA tube) or extracted DNA. Confirm specific requirements with the laboratory before booking.
MethodologyNext Generation Sequencing (NGS) is used to analyze the IRF8 gene for disease-causing mutations.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically targets the IRF8 gene. It may not detect mutations in other genes that can cause similar symptoms. A negative result does not completely rule out an immunodeficiency disorder. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

This is a rare genetic disorder affecting the immune system, specifically the function of monocytes and dendritic cells, leading to increased susceptibility to infections.
Individuals with recurrent infections, a family history of immunodeficiency, or clinical signs suggesting a primary immune disorder should discuss this test with their doctor.
A positive result indicates the presence of mutations in the IRF8 gene associated with Immunodeficiency Type 32B. Discuss the implications with your healthcare provider.
Yes, genetic counseling is highly recommended before and after testing to understand the risks, benefits, and implications of the results.
A blood sample is typically required for this test. Confirm specific sample requirements with the laboratory.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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