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Medical information Clinical review pending

Genetic Testing

ISG15 Gene Immunodeficiency Type 38 Genetic Test

Genetic test using Next-Generation Sequencing (NGS) to identify mutations in the ISG15 gene associated with immunodeficiency disorders. Helps understand the cause of immunological issues.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube) or extracted DNA. Confirm specific requirements with the laboratory before booking.
Results
Confirm with the laboratory before booking.
Preparation
No special preparation is typically required for a blood draw. Follow any specific instructions provided by the laboratory or your doctor.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the ISG15 Gene Immunodeficiency Type 38 Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Recurrent infections
  • ✓Autoimmune disorders
  • ✓Unexplained immunological issues
  • ✓Family history of immunodeficiency
  • ✓Suspected primary immunodeficiency
  • ✓Evaluation of immune system dysfunction
02

In plain language

What this test helps you understand

Identifies mutations in the ISG15 gene, which can cause specific immunodeficiency disorders. This information aids in diagnosis, understanding disease mechanisms, and guiding treatment strategies.
The ISG15 Gene Immunodeficiency Type 38 NGS Genetic DNA Test is a diagnostic tool used to identify specific genetic mutations linked to certain immunodeficiency disorders. This test uses Next-Generation Sequencing (NGS) technology to analyze the ISG15 gene, which is important for immune function.

This test looks for changes within the ISG15 gene that can cause problems with the immune system. Finding these changes can help doctors understand why a patient is experiencing certain symptoms and guide treatment decisions.

Individuals with recurrent infections, autoimmune conditions, or other unexplained immune system problems might be candidates for this test. People with a family history of immunodeficiency disorders may also consider testing to understand their genetic risk.

Benefits of this test include accurate identification of relevant genetic mutations, support for personalized treatment strategies, and information for genetic counseling and family planning. Early detection can potentially lead to better management of health complications.

Results are typically available within 3 to 4 weeks. A genetic counselor can help explain the results and discuss what they mean for your health and potential next steps.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is typically required for a blood draw. Follow any specific instructions provided by the laboratory or your doctor.
SampleBlood sample (EDTA tube) or extracted DNA. Confirm specific requirements with the laboratory before booking.
MethodologyNext-Generation Sequencing (NGS) of the ISG15 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically analyzes the ISG15 gene. It may not detect mutations in other genes that can cause similar symptoms. Results need to be interpreted in the context of clinical findings and family history. A negative result does not completely rule out all genetic causes of immunodeficiency.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

The ISG15 gene provides instructions for making a protein involved in the immune response, particularly in fighting viral infections.
This test detects specific genetic mutations (changes) within the ISG15 gene that are known to cause certain types of immunodeficiency.
Individuals experiencing recurrent infections, autoimmune problems, or other signs of immune system dysfunction, especially if there's a family history, may be recommended for this test.
Results are interpreted by specialists, often in conjunction with your doctor. Genetic counseling is recommended to understand the implications of the findings.
Genetic counseling is recommended for patients undergoing this test to help understand the results and their implications. Please confirm availability and cost with the laboratory.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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