Skip to main content
Medical information Clinical review pending

Genetic Testing

Methylenetetrahydrofolate Reductase MTHFR Factor V F5 Factor II F2

Genetic test assessing mutations in MTHFR, Factor V (F5), and Factor II (F2) genes linked to thrombotic disorders and homocysteine metabolism. Helps identify potential increased risk for blood clots.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

Ask a question
Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Peripheral blood sample collected in an EDTA Vacutainer tube (2ml).
Results
Confirm with the laboratory before booking.
Preparation
A doctor’s prescription is required for this test, except for specific cases such as pre-surgery, pregnancy, or planned international travel. Confirm with the laboratory before booking.
Test priceKSh 24,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Methylenetetrahydrofolate Reductase MTHFR Factor V F5 Factor II F2 test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

+254

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Personal or family history of blood clots (thrombosis)
  • ✓Unexplained thrombotic events
  • ✓Elevated homocysteine levels
  • ✓Planning for major surgery
  • ✓Planning international travel
  • ✓Pregnancy planning or history of pregnancy complications related to clotting
02

In plain language

What this test helps you understand

This test helps identify genetic variations in MTHFR, F5, and F2 genes that may be associated with an increased risk of thrombotic disorders (blood clots) and elevated homocysteine levels. Understanding these genetic predispositions can inform preventive strategies and management plans.
The Methylenetetrahydrofolate Reductase (MTHFR), Factor V (F5), and Factor II (F2) test is a genetic assessment designed to identify specific mutations in genes associated with blood clotting and homocysteine levels. Understanding these genetic factors can be important for individuals concerned about their risk of thrombotic events, such as deep vein thrombosis (DVT) or pulmonary embolism (PE). This test examines variations in the MTHFR, F5, and F2 genes, which play roles in blood coagulation and the metabolism of homocysteine, an amino acid linked to cardiovascular health. Identifying certain mutations may help individuals and their healthcare providers understand potential predispositions and make informed decisions about health management. This test is particularly relevant for those with a personal or family history of blood clots or related conditions. Results require interpretation by a healthcare professional to understand their implications for individual health.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationA doctor’s prescription is required for this test, except for specific cases such as pre-surgery, pregnancy, or planned international travel. Confirm with the laboratory before booking.
SamplePeripheral blood sample collected in an EDTA Vacutainer tube (2ml).
MethodologyGenetic analysis using molecular techniques to detect specific variations in the MTHFR, F5, and F2 genes.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test identifies specific genetic mutations but does not guarantee the development of thrombotic disorders. Other genetic and environmental factors also play a role. Results should be interpreted by a healthcare professional.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

This test looks for specific genetic mutations in the MTHFR, Factor V (F5), and Factor II (F2) genes, which are associated with blood clotting and homocysteine metabolism.
Individuals with a personal or family history of blood clots, unexplained clotting events, elevated homocysteine levels, or those planning surgery or international travel may benefit from this test.
Results indicate the presence or absence of specific genetic mutations. A healthcare provider must interpret these results in the context of your overall health and family history.
Yes, a doctor’s prescription is generally required for this test. Exceptions may apply for pre-surgery, pregnancy, or international travel planning. Please confirm with the laboratory.
The sample is a peripheral blood draw collected in a specific type of tube (EDTA Vacutainer).
Turnaround time varies. Please confirm the current estimated turnaround time with the laboratory before booking.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

Keep exploring

Related tests

View all tests →
Chat on WhatsApp