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Medical information Clinical review pending

Genetic Testing

Microsatellite Instability MSI PCR Test

The Microsatellite Instability (MSI) PCR Test checks for genetic changes in tumor cells, helping guide cancer treatment, especially immunotherapy. Recommended for individuals with certain cancer types or family history.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Formalin-Fixed Paraffin-Embedded (FFPE) tissue block from the tumor.
Results
Confirm with the laboratory before booking.
Preparation
No special patient preparation is required for this test.
Test priceKSh 32,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Microsatellite Instability MSI PCR Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Patients diagnosed with colorectal cancer.
  • ✓Patients diagnosed with endometrial cancer.
  • ✓Individuals with a strong family history of colorectal or endometrial cancer.
  • ✓Patients with certain rare genetic syndromes.
  • ✓Patients whose cancer treatment options are being evaluated.
02

In plain language

What this test helps you understand

This test helps identify patients with microsatellite instability (MSI) in their tumors. This information is crucial for guiding treatment decisions, particularly regarding the use of immunotherapy, and for understanding prognosis.
The Microsatellite Instability (MSI) PCR Test is a diagnostic tool used to evaluate genetic instability in tumors. This instability is often linked to specific cancers, such as colorectal and endometrial cancers. The test helps identify patients who might benefit from particular treatments, including immunotherapy. By detecting microsatellite instability, healthcare providers can gain a better understanding of the cancer's genetic makeup and tailor treatment plans more effectively.

This test assesses the stability of microsatellite regions in the DNA of tumor cells. It looks for variations in specific markers: BAT 25, BAT 26, D2S123, D17S250, and D5S346. The presence of instability in these regions can indicate certain genetic conditions or cancer susceptibility.

This test is often recommended for individuals with a family history of cancer, particularly colorectal and endometrial cancers, patients experiencing symptoms like unexplained weight loss or changes in bowel habits, or those already diagnosed with cancer who are exploring treatment options. Discussing this test with an oncologist is advisable if you fit these criteria.

Understanding the results involves determining if microsatellite instability is present. A positive result can provide valuable information for personalized treatment strategies and prognosis. It's crucial to discuss your results with your oncologist to understand their implications and next steps.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special patient preparation is required for this test.
SampleFormalin-Fixed Paraffin-Embedded (FFPE) tissue block from the tumor.
MethodologyPolymerase Chain Reaction (PCR) analysis to detect variations in specific microsatellite markers (BAT 25, BAT 26, D2S123, D17S250, D5S346).
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test requires adequate quality and quantity of FFPE tissue. Results may be affected by poor tissue quality or insufficient tumor content. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

MSI is a condition where there are changes in the length of short DNA sequences called microsatellites. This instability can be a sign of certain genetic conditions or cancers.
Knowing if a tumor has MSI helps doctors choose the most effective treatments. For example, MSI-High tumors often respond well to immunotherapy.
The test requires a sample of FFPE tissue, which is typically obtained from a tumor biopsy or surgery.
Confirm with the laboratory before booking.
Results will indicate whether MSI is present (MSI-High or MSI-Low/MSS). Your doctor will interpret these results in the context of your overall health and diagnosis.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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