Medical information Clinical review pending

Genetic Testing

MMAB Gene Methylmalonic Aciduria CblB Type Genetic Test

Genetic test to identify mutations in the MMAB gene associated with Methylmalonic aciduria (CblB type), a metabolic disorder. Aids in diagnosis and management.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube) or extracted DNA. A dried blood spot on an FTA card may also be acceptable. Confirm specific requirements with the laboratory before booking.
Results: Results are typically available within 3 to 4 weeks. Confirm exact turnaround time with the laboratory before booking.
Preparation: No specific patient preparation is required for the blood draw. However, providing a detailed clinical history and family history (pedigree chart if possible) is essential for accurate interpretation. A pre-test genetic counseling session is recommended.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the MMAB Gene Methylmalonic Aciduria CblB Type Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Individuals with symptoms suggestive of a metabolic disorder (e.g., developmental delay, neurological issues, vomiting).
✓Patients with elevated levels of methylmalonic acid in blood or urine.
✓Newborns screened positive for metabolic disorders.
✓Individuals with a family history of Methylmalonic aciduria.
✓Confirmation of diagnosis before initiating specific therapies.

In plain language

What this test helps you understand

This test helps diagnose Methylmalonic aciduria (CblB type) by identifying mutations in the MMAB gene. It can confirm a suspected diagnosis based on clinical symptoms or biochemical findings, guide appropriate treatment and dietary management, and provide information for genetic counseling and family planning.

The MMAB Gene Methylmalonic Aciduria CblB Type NGS Genetic DNA Test is a diagnostic tool used to detect mutations in the MMAB gene. These mutations can cause Methylmalonic aciduria, a metabolic disorder affecting the body's ability to process certain amino acids and fats. This test uses Next Generation Sequencing (NGS) technology for accurate results. Early diagnosis is important for managing this condition effectively. Understanding the genetic basis of the disorder can help guide treatment and dietary management strategies. Genetic counseling is often recommended to discuss the implications of the results and inheritance patterns within a family.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationNo specific patient preparation is required for the blood draw. However, providing a detailed clinical history and family history (pedigree chart if possible) is essential for accurate interpretation. A pre-test genetic counseling session is recommended.

SampleBlood sample (EDTA tube) or extracted DNA. A dried blood spot on an FTA card may also be acceptable. Confirm specific requirements with the laboratory before booking.

MethodologyNext Generation Sequencing (NGS) is used to analyze the MMAB gene for pathogenic variants.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test specifically analyzes the MMAB gene. It may not detect mutations in other genes that can cause similar symptoms. Results may be classified as variants of uncertain significance (VUS), requiring further investigation. The test does not guarantee prediction of disease severity or response to treatment.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

It is a metabolic disorder caused by defects in the MMAB gene, affecting the body's ability to break down certain proteins and fats, leading to a buildup of methylmalonic acid.

Early diagnosis allows for timely management, including dietary changes and potential treatments, which can significantly improve health outcomes.

A blood sample is typically required. Confirm the exact specimen type and collection instructions with the laboratory.

The turnaround time is approximately 3 to 4 weeks, but this can vary. Please confirm the current turnaround time with the laboratory.

Yes, the results can help determine the inheritance pattern and assess the risk for family members. Genetic counseling is recommended to discuss these implications.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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