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Genetic Testing

MRPS22 Gene Combined Oxidative Phosphorylation Deficiency Type 5 Genetic Test

Genetic test using Next-Generation Sequencing (NGS) to analyze the MRPS22 gene for mutations associated with Combined Oxidative Phosphorylation Deficiency Type 5, a metabolic disorder. Recommended for individuals with relevant symptoms or family history.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube). Confirm with the laboratory before booking.
Results: Confirm with the laboratory before booking.
Preparation: No specific patient preparation is required, but a clinical history review and genetic counseling session are advised before the test.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the MRPS22 Gene Combined Oxidative Phosphorylation Deficiency Type 5 Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Mobile number *

+254

Insurer or scheme

Policy / member number (optional)

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Unexplained metabolic issues
✓Muscle weakness
✓Neurological problems
✓Developmental delays
✓Family history of metabolic disorders
✓Symptoms suggestive of mitochondrial dysfunction

In plain language

What this test helps you understand

This test helps identify mutations in the MRPS22 gene, which are associated with Combined Oxidative Phosphorylation Deficiency Type 5. This information can aid in the diagnosis of metabolic disorders related to mitochondrial dysfunction.

The MRPS22 Gene Combined Oxidative Phosphorylation Deficiency Type 5 NGS Genetic DNA Test is a diagnostic tool used to identify genetic mutations linked to metabolic disorders. This test employs Next-Generation Sequencing (NGS) technology to examine the MRPS22 gene, which is important for mitochondrial function. Understanding genetic factors can inform treatment and lifestyle decisions. This test specifically assesses the MRPS22 gene, crucial for mitochondrial ribosome assembly. Identifying mutations helps diagnose conditions related to oxidative phosphorylation deficiencies. Consider this test if you have unexplained metabolic issues, muscle weakness, neurological problems, or developmental delays. It is also recommended for individuals with a family history of metabolic disorders affecting mitochondrial function or those advised by a healthcare provider after genetic counseling. Benefits include accurate diagnosis for timely intervention, personalized treatment plans, and better understanding of hereditary conditions for family planning. Results will indicate the presence of mutations in the MRPS22 gene. A genetic counselor will help interpret the results, and discussion with a healthcare provider is essential to determine next steps. We have branches in Nairobi, Mombasa, and Kisumu, and offer home sample collection. Please call or WhatsApp +254711564616 to book. Before the test, a clinical history review and genetic counseling session are advised to understand your family's genetic background.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationNo specific patient preparation is required, but a clinical history review and genetic counseling session are advised before the test.

SampleBlood sample (EDTA tube). Confirm with the laboratory before booking.

MethodologyNext-Generation Sequencing (NGS) of the MRPS22 gene.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test only analyzes the MRPS22 gene. It may not detect mutations in other genes associated with similar conditions. A negative result does not completely rule out a genetic disorder. Confirm with the laboratory before booking.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

This is a metabolic disorder caused by mutations in the MRPS22 gene, affecting the function of mitochondria, which are responsible for energy production in cells.

Individuals with symptoms like muscle weakness, neurological issues, or developmental delays, or those with a family history of similar conditions, may be advised to take this test.

The test uses advanced NGS technology for accurate detection of mutations in the MRPS22 gene. However, it's important to discuss the results with a healthcare provider.

Results will be interpreted by a genetic counselor and discussed with your healthcare provider to determine the appropriate next steps, such as treatment or further investigation.

Yes, genetic counseling before and after the test is strongly recommended to understand the implications of the results and discuss family planning.

You can book the test by calling or WhatsApping us at +254711564616. We have branches in Nairobi, Mombasa, and Kisumu, and offer home sample collection.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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