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Medical information Clinical review pending

Genetic Testing

MTCO1 Gene Cytochrome C Oxidase 1 Deficiency Genetic Test

Genetic test for MTCO1 gene mutations, identifying cytochrome c oxidase deficiency linked to mitochondrial neurological disorders. Uses Next-Generation Sequencing (NGS).

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube). Confirm specific requirements with the laboratory before booking.
Results
3 to 4 weeks. Confirm with the laboratory before booking.
Preparation
No special preparation is typically required. Confirm with the laboratory before booking.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the MTCO1 Gene Cytochrome C Oxidase 1 Deficiency Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Unexplained neurological disorders
  • ✓Muscle weakness
  • ✓Seizures
  • ✓Cognitive decline
  • ✓Severe fatigue
  • ✓Family history of mitochondrial disease
02

In plain language

What this test helps you understand

Identifies mutations in the MTCO1 gene associated with cytochrome c oxidase deficiency, aiding in the diagnosis of mitochondrial neurological disorders. Helps guide treatment decisions and family planning.
The MTCO1 Gene Cytochrome C Oxidase 1 Deficiency NGS Genetic DNA Test is a specialized diagnostic tool used to identify mitochondrial disorders, particularly those affecting neurological functions. This test utilizes advanced Next-Generation Sequencing (NGS) technology to analyze the MTCO1 gene. This gene provides instructions for making cytochrome c oxidase, an essential enzyme involved in cellular respiration, the process cells use to generate energy. Mutations in the MTCO1 gene can lead to cytochrome c oxidase deficiency, causing a range of symptoms. This test detects specific mutations within the MTCO1 gene. Identifying these mutations helps healthcare providers understand the underlying cause of neurological symptoms and guide appropriate management strategies. Results are typically available within 3 to 4 weeks. A genetic counselor or healthcare professional will assist in interpreting the results and discussing their implications.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is typically required. Confirm with the laboratory before booking.
SampleBlood sample (EDTA tube). Confirm specific requirements with the laboratory before booking.
MethodologyNext-Generation Sequencing (NGS) of the MTCO1 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically analyzes the MTCO1 gene. It may not detect mutations in other genes associated with similar conditions. Results must be interpreted in the context of clinical findings and family history. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

The MTCO1 gene provides instructions for making a part of the cytochrome c oxidase enzyme complex, which is essential for cellular energy production.
This test detects mutations (changes) in the MTCO1 gene that can cause cytochrome c oxidase deficiency, a type of mitochondrial disorder.
Individuals with symptoms like unexplained neurological issues, muscle weakness, seizures, cognitive decline, or a family history of mitochondrial diseases may be candidates for this test.
A healthcare professional or genetic counselor will interpret the results in the context of your medical history and symptoms to determine the significance of any findings.
Results are typically available within 3 to 4 weeks, but this timeframe can vary. Confirm with the laboratory before booking.
Yes, this test requires a blood sample. Specific collection instructions will be provided by the laboratory.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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