Medical information Clinical review pending

Genetic Testing

MTND1 Gene Mitochondrial Complex I Deficiency Genetic Test

Genetic test using Next-Generation Sequencing (NGS) to identify mutations in the MTND1 gene, associated with mitochondrial complex I deficiency and neurological disorders.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube), Extracted DNA, or One drop of blood on FTA card.
Results: Confirm with the laboratory before booking.
Preparation: Discuss your medical history and family history, particularly any neurological conditions or mitochondrial diseases, with your doctor. A genetic counseling session may be recommended prior to testing to understand the implications and create a family pedigree. Confirm specific preparation instructions with the laboratory before booking.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the MTND1 Gene Mitochondrial Complex I Deficiency Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Individuals with symptoms suggestive of mitochondrial disease (e.g., muscle weakness, developmental delay, seizures).
✓Patients with unexplained neurological disorders.
✓Family history of mitochondrial disease or related conditions.
✓Inconclusive results from previous genetic testing.
✓Assessment of genetic risk for mitochondrial disorders.

In plain language

What this test helps you understand

This test helps identify mutations in the MTND1 gene, which are linked to mitochondrial complex I deficiency. Identifying these mutations can aid in diagnosing mitochondrial disorders, understanding the underlying cause of neurological symptoms, and guiding management strategies. It can also provide information for genetic counseling regarding inheritance patterns within families.

The MTND1 Gene Mitochondrial Complex I Deficiency NGS Genetic DNA Test is a diagnostic tool used to identify specific genetic changes in the MTND1 gene. This gene provides instructions for making a protein that is part of Complex I, a crucial component of the mitochondria responsible for energy production within cells. Mutations in this gene can lead to mitochondrial complex I deficiency, which may cause a variety of neurological and other health problems. This test utilizes advanced Next-Generation Sequencing (NGS) technology for a comprehensive analysis. Understanding the genetic basis of mitochondrial disorders is vital for accurate diagnosis, management, and genetic counseling.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationDiscuss your medical history and family history, particularly any neurological conditions or mitochondrial diseases, with your doctor. A genetic counseling session may be recommended prior to testing to understand the implications and create a family pedigree. Confirm specific preparation instructions with the laboratory before booking.

SampleBlood sample (EDTA tube), Extracted DNA, or One drop of blood on FTA card.

MethodologyNext-Generation Sequencing (NGS) is used to analyze the MTND1 gene for mutations.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test specifically analyzes the MTND1 gene. It may not detect mutations in other genes associated with mitochondrial disorders or other causes of the patient's symptoms. A negative result does not completely rule out a mitochondrial disorder. Confirm with the laboratory before booking.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

The MTND1 gene contains instructions for making a protein essential for mitochondrial function, specifically Complex I, which is involved in energy production.

This is a condition where the Complex I enzyme in mitochondria does not function properly, leading to reduced energy production and potentially causing various health issues, often affecting the nervous system.

Individuals with symptoms like muscle weakness, developmental delays, seizures, or a family history of mitochondrial diseases may be candidates for this test.

A positive result indicates the presence of mutations in the MTND1 gene associated with mitochondrial complex I deficiency. Further consultation with a healthcare provider is needed to interpret the findings.

A negative result means no mutations associated with MTND1-related mitochondrial complex I deficiency were detected in the tested sample. It does not rule out other genetic causes or mitochondrial disorders.

Results should be interpreted by a qualified healthcare professional, often in consultation with a geneticist or genetic counselor, considering the patient's clinical presentation and family history.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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