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Genetic Testing

Nx Gen Sequencing Microphtahlmia Anophthalmia Coloboma Spectrum Test

The Nx Gen Sequencing Microphtahlmia Anophthalmia Coloboma Spectrum Test uses advanced genetic analysis to identify the causes of specific eye defects like microphtahlmia, anophthalmia, and coloboma. This test helps in understanding the genetic basis of these conditions.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
10 mL (5 mL minimum) whole blood collected in two Lavender Top (EDTA) tubes.
Results
Confirm with the laboratory before booking.
Preparation
No special preparation is required for the patient. A duly filled Whole Exome Sequencing Consent Form (Form 37) is mandatory.
Test priceKSh 57,330

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Nx Gen Sequencing Microphtahlmia Anophthalmia Coloboma Spectrum Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Diagnosis of suspected genetic eye disorders
  • ✓Individuals with microphtahlmia (abnormally small eyes)
  • ✓Individuals with anophthalmia (absence of eyes)
  • ✓Individuals with coloboma (eye structure defect)
  • ✓Family history of congenital eye defects
  • ✓Genetic counseling for family planning
02

In plain language

What this test helps you understand

This test identifies genetic mutations associated with microphtahlmia, anophthalmia, and coloboma, aiding in diagnosis, treatment planning, and genetic counseling.
The Nx Gen Sequencing Microphtahlmia Anophthalmia Coloboma Spectrum Test is a state-of-the-art genetic test that utilizes Next Generation Sequencing (NGS) technology to identify genetic mutations associated with various eye defects, including microphtahlmia, anophthalmia, and coloboma. Understanding these defects is crucial for timely diagnosis and management, allowing for better treatment outcomes.

This test specifically measures mutations in a comprehensive panel of genes known to be associated with eye development. Key components analyzed include ABCB6, ALDH1A3, BCOR, BMP4, CHD7, ERCC1, ERCC2, ERCC5, ERCC6, FOXE3, FOXL2, FRAS1, FREM1, FREM2, GDF3, GDF6, GJA1, GRIP1, HCCS, HESX1, HMGB3, HMX1, MAB21L2, MFRP, NAA10, NDP, OCRL, OTX2, PAX2, PAX6, PRSS56, PXDN, RAB18, RAB3GAP1, RAB3GAP2, RARB, RAX, RBP4, SALL2, SALL4, SHH, SIX3, SIX6, SMOC1, SOX2, STRA6, TBC1D20, TENM3, TFAP2A, VAX1, and VSX2.

This test is recommended for individuals exhibiting symptoms or having a family history of eye defects such as microphtahlmia (abnormally small eyes), anophthalmia (absence of one or both eyes), or coloboma (a defect in the eye structure). It is also recommended for those with a family history of congenital eye defects.

Benefits of taking this test include accurate diagnosis of genetic eye disorders, informed decision-making regarding treatment options, understanding potential hereditary risks for family planning, and access to specialized care and support services.

Results from the Nx Gen Sequencing Test will provide insights into the specific genetic mutations present. A genetic counselor will help interpret the results and discuss potential implications for treatment and family planning.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is required for the patient. A duly filled Whole Exome Sequencing Consent Form (Form 37) is mandatory.
Sample10 mL (5 mL minimum) whole blood collected in two Lavender Top (EDTA) tubes.
MethodologyNext Generation Sequencing (NGS)
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test analyzes a specific panel of genes associated with microphtahlmia, anophthalmia, and coloboma. It may not detect mutations in genes not included in the panel or other genetic causes of eye defects. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Microphtahlmia is a condition where the eyes are abnormally small. Anophthalmia is the absence of one or both eyes. Coloboma is a gap or defect in one of the structures of the eye, such as the iris, retina, choroid, or optic nerve.
Individuals diagnosed with or suspected of having microphtahlmia, anophthalmia, or coloboma, as well as those with a family history of these conditions, should consider this test.
The test involves analyzing a sample of your blood to look for specific genetic mutations associated with eye development disorders.
A genetic counselor will help interpret the test results and discuss their implications for your health, treatment options, and potential risks for family members.
Insurance coverage varies. Please check with your insurance provider regarding coverage for genetic testing.
Turnaround time can vary. Please confirm the current turnaround time with the laboratory before booking.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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