Medical information Clinical review pending

Genetic Testing

PMS2 Gene Mismatch Repair Cancer Syndrome Genetic Test

The PMS2 Gene Mismatch Repair Cancer Syndrome Genetic Test identifies mutations in the PMS2 gene, linked to an increased risk of certain cancers like Lynch syndrome. This test helps individuals understand their genetic predisposition for proactive health management.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

Ask a question

Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
Results: Approximately 3 to 4 weeks. Confirm with the laboratory before booking.
Preparation: A clinical history of the patient is required. A genetic counseling session is recommended prior to testing to create a pedigree chart of family members affected by PMS2 gene-related conditions.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the PMS2 Gene Mismatch Repair Cancer Syndrome Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

Full name *

Mobile number *

+254

Insurer or scheme

Policy / member number (optional)

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

WhatsApp the claims team Call us

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Family history of colorectal cancer or Lynch syndrome-associated cancers.
✓Personal history of cancer at a young age.
✓Multiple primary cancers in an individual.
✓Seeking to understand genetic risk factors for cancer.
✓Family history suggestive of hereditary cancer syndrome.

In plain language

What this test helps you understand

Identifies mutations in the PMS2 gene associated with hereditary cancer syndromes, particularly Lynch syndrome, enabling risk assessment and proactive health management.

The PMS2 Gene Mismatch Repair Cancer Syndrome NGS Genetic DNA Test is a specialized genetic test designed to detect mutations in the PMS2 gene. These mutations are associated with hereditary non-polyposis colorectal cancer (Lynch syndrome) and other cancers. This test plays a vital role in identifying individuals who may be at an increased risk for developing certain types of cancer, allowing for proactive health management and early intervention. This test utilizes Next-Generation Sequencing (NGS) technology to analyze the PMS2 gene for specific mutations. By identifying these genetic alterations, healthcare providers can assess a patient’s risk for developing cancers linked to PMS2 gene deficiencies. Understanding your genetic predisposition aids in making informed health decisions and guides family planning and screening strategies for relatives. Results will indicate whether mutations are present in the PMS2 gene. A healthcare provider will guide you in interpreting these results and discussing implications for your health and potential monitoring or preventive strategies.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationA clinical history of the patient is required. A genetic counseling session is recommended prior to testing to create a pedigree chart of family members affected by PMS2 gene-related conditions.

SampleBlood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.

MethodologyNext-Generation Sequencing (NGS) is used to analyze the PMS2 gene for mutations.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test specifically analyzes the PMS2 gene. It does not detect mutations in other genes associated with cancer risk. Results must be interpreted in the context of personal and family history by a qualified healthcare professional. Confirm with the laboratory before booking.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

The PMS2 gene provides instructions for making a protein that helps correct errors that occur when DNA is copied. Mutations in this gene can lead to an increased risk of certain cancers.

Lynch syndrome, also known as hereditary non-polyposis colorectal cancer (HNPCC), is an inherited disorder that increases the risk of many types of cancer, particularly colorectal cancer. PMS2 mutations are a common cause of Lynch syndrome.

Individuals with a family history of colorectal cancer or other Lynch syndrome-associated cancers, or those diagnosed with cancer at a young age, may be candidates for this test. Discuss with your doctor.

Your doctor will discuss the results with you. If a mutation is found, it may lead to recommendations for increased cancer screening or preventive measures. Genetic counseling is often recommended.

Insurance coverage varies. Please check with your insurance provider regarding coverage for genetic testing.

You can book the test by calling or WhatsApping us at +254711564616. We have branches across major cities in Kenya.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

Keep exploring

Related tests

View all tests →

Chat on WhatsApp