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Medical information Clinical review pending

Genetic Testing

STAT3 Gene HyperIgE Recurrent Infection Syndrome Genetic Test

Genetic test using Next Generation Sequencing (NGS) to identify mutations in the STAT3 gene associated with Hyper-IgE Syndrome, a rare immunological disorder characterized by recurrent infections and eczema.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube). Confirm specific requirements with the laboratory before booking.
Results
Confirm turnaround time with the laboratory before booking.
Preparation
No special preparation is typically required for this blood test. However, confirm with the laboratory for any specific instructions.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the STAT3 Gene HyperIgE Recurrent Infection Syndrome Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Recurrent skin infections
  • ✓Severe eczema
  • ✓Frequent respiratory infections
  • ✓Family history of Hyper-IgE Syndrome
  • ✓Suspected primary immunodeficiency
  • ✓Evaluation of immunological disorders
02

In plain language

What this test helps you understand

This test helps identify genetic mutations in the STAT3 gene associated with Hyper-IgE Syndrome, aiding in the diagnosis of this rare immunological disorder. It can inform clinical management and potential treatment strategies.
The STAT3 Gene HyperIgE Recurrent Infection Syndrome NGS Genetic DNA Test is a diagnostic tool used to identify mutations in the STAT3 gene. These mutations are linked to Hyper-IgE syndrome, a rare condition affecting the immune system. This syndrome often presents with recurrent infections, severe eczema, and high levels of Immunoglobulin E (IgE). Understanding a potential genetic link can be important for managing the condition effectively.

This test employs Next Generation Sequencing (NGS) technology to analyze DNA for specific changes in the STAT3 gene. Identifying these genetic markers allows healthcare providers to make informed decisions about diagnosis and treatment, potentially leading to earlier intervention and personalized care plans.

If you or a family member experience frequent or severe infections, particularly skin or respiratory infections, along with eczema, or if there is a family history of similar conditions, discussing this test with a doctor may be beneficial.

Understanding the results requires consultation with a healthcare professional who can interpret the findings in the context of your clinical history and provide appropriate guidance.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is typically required for this blood test. However, confirm with the laboratory for any specific instructions.
SampleBlood sample (EDTA tube). Confirm specific requirements with the laboratory before booking.
MethodologyNext Generation Sequencing (NGS) of the STAT3 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically analyzes the STAT3 gene. It does not detect mutations in other genes that may cause similar symptoms. A negative result does not completely rule out Hyper-IgE Syndrome or other immunological disorders. Interpretation requires clinical correlation.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Hyper-IgE Syndrome is a rare primary immunodeficiency disorder characterized by recurrent infections, eczema, and high levels of IgE. It can be caused by mutations in genes like STAT3.
Individuals with recurrent skin or respiratory infections, severe eczema, or a family history of similar conditions should discuss this test with their doctor.
The test involves analyzing a blood sample using Next Generation Sequencing (NGS) to look for specific mutations in the STAT3 gene.
Results indicate the presence or absence of specific STAT3 gene mutations. A healthcare provider will interpret these results in the context of your clinical history.
Insurance coverage varies. Please check with your insurance provider regarding coverage for genetic testing.
You can contact the laboratory via phone or WhatsApp at +254711564616 to book the test or inquire about online booking options.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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