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Medical information Clinical review pending

Genetic Testing

STX11 Gene Hemophagocytic Lymphohistiocytosis Type 4 Genetic Test

Genetic test to identify mutations in the STX11 gene associated with Hemophagocytic Lymphohistiocytosis (HLH), a severe immune disorder. Helps in early diagnosis and management.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
A blood sample is required for this test. Please confirm specific collection requirements with the laboratory before booking.
Results
Confirm with the laboratory before booking.
Preparation
No special preparation is typically required for this blood test. However, it is always best to confirm with the laboratory.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the STX11 Gene Hemophagocytic Lymphohistiocytosis Type 4 Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Suspected diagnosis of Hemophagocytic Lymphohistiocytosis (HLH).
  • ✓Family history of HLH or related immune disorders.
  • ✓Presence of symptoms suggestive of HLH (e.g., persistent fever, enlarged spleen, low blood cell counts).
  • ✓Unexplained immunological abnormalities.
  • ✓Genetic counseling for families with a history of HLH.
02

In plain language

What this test helps you understand

This test helps identify specific genetic mutations in the STX11 gene that are known to cause Hemophagocytic Lymphohistiocytosis Type 4. This information can confirm a diagnosis, help understand the underlying cause of the condition, and potentially guide treatment strategies. It can also be used for genetic counseling within families.
The STX11 Gene Hemophagocytic Lymphohistiocytosis Type 4 NGS Genetic DNA Test is a diagnostic tool used to identify genetic mutations linked to Hemophagocytic Lymphohistiocytosis (HLH). HLH is a rare, life-threatening condition where the immune system becomes overactive. This test uses Next Generation Sequencing (NGS) technology to analyze the STX11 gene, which is involved in regulating immune responses. Identifying mutations in this gene can help diagnose HLH, understand genetic risks, and guide treatment decisions. Early detection is crucial for managing this condition effectively.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is typically required for this blood test. However, it is always best to confirm with the laboratory.
SampleA blood sample is required for this test. Please confirm specific collection requirements with the laboratory before booking.
MethodologyNext Generation Sequencing (NGS) is used to analyze the STX11 gene for mutations.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically analyzes the STX11 gene. It does not detect mutations in other genes associated with HLH. A negative result does not completely rule out HLH, as other genetic or non-genetic causes may be involved. Interpretation of results should be done in conjunction with clinical findings.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

HLH is a rare and serious immune disorder where the body's immune cells become overactive, leading to widespread inflammation and organ damage.
The STX11 gene provides instructions for making a protein involved in the function of immune cells, particularly cytotoxic T lymphocytes and natural killer cells.
Individuals with symptoms suggestive of HLH, a family history of HLH, or unexplained immune system problems may be recommended for this test.
Results are interpreted by genetic specialists in the context of your clinical history. Genetic counseling is often recommended to understand the implications.
Insurance coverage varies. Please check with your insurance provider regarding coverage for genetic testing.
This test is available at DNA Labs Kenya branches in Nairobi, Mombasa, and Kisumu. Home sample collection may also be an option.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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