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Medical information Clinical review pending

Genetic Testing

Tacrolimus Genotyping CYP3A5 Test

The Tacrolimus Genotyping CYP3A5 Test helps personalize Tacrolimus medication dosage for organ transplant patients by identifying genetic variations affecting drug metabolism. This aids in optimizing treatment and reducing side effects.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
3 ml (2 ml minimum) whole blood collected in a Lavender top (EDTA) tube.
Results
Results are typically reported on Wednesdays and Saturdays. Confirm current turnaround time with the laboratory before booking.
Preparation
No special preparation is required for this test.
Test priceKSh 14,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Tacrolimus Genotyping CYP3A5 Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Patients prescribed Tacrolimus after organ transplantation.
  • ✓Individuals experiencing unexpected side effects with Tacrolimus.
  • ✓Patients with suboptimal response to standard Tacrolimus doses.
  • ✓Monitoring Tacrolimus therapy in transplant recipients.
02

In plain language

What this test helps you understand

This test helps guide Tacrolimus dosing based on individual genetic makeup, potentially improving therapeutic outcomes and reducing the risk of toxicity in transplant patients.
The Tacrolimus Genotyping CYP3A5 Test is a genetic analysis designed to understand how your body processes Tacrolimus. Tacrolimus is a medication commonly used after organ transplants to prevent the body from rejecting the new organ. This test looks for specific variations in the CYP3A5 gene, which plays a key role in breaking down Tacrolimus. Knowing your CYP3A5 genotype helps your doctor determine the right dose of Tacrolimus for you, potentially improving treatment effectiveness and minimizing adverse reactions. This test is particularly useful for individuals undergoing kidney or other organ transplants who are taking Tacrolimus. Discuss with your healthcare provider if this test is appropriate for you.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is required for this test.
Sample3 ml (2 ml minimum) whole blood collected in a Lavender top (EDTA) tube.
MethodologyGenetic analysis of the CYP3A5 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test analyzes specific variations in the CYP3A5 gene. Other genetic factors and non-genetic factors (like other medications or liver function) can also influence Tacrolimus metabolism. Results should be interpreted in the context of the patient's overall clinical picture.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Tacrolimus is an immunosuppressant medication used to prevent organ rejection after transplantation.
It helps determine the right dose of Tacrolimus based on your genetics, improving treatment effectiveness and reducing side effects.
Typically, patients taking Tacrolimus after an organ transplant may benefit from this test.
A simple blood draw is required for this test.
Results are usually available on Wednesdays and Saturdays. Please confirm the current turnaround time with the lab.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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