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Medical information Clinical review pending

Genetic Testing

TLR5 Gene Legionnaire Disease Susceptibility to Genetic Test

This genetic test assesses your predisposition to Legionnaire disease by analysing variations in the TLR5 gene, which influences immune response to the Legionella bacterium. It's particularly relevant for those with a family history or specific health concerns.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube), extracted DNA, or dried blood spot on an FTA card.
Results
Confirm with the laboratory before booking.
Preparation
A detailed clinical history of the patient is required. A genetic counselling session is recommended prior to testing to discuss the test's purpose, limitations, and potential implications, including creating a family pedigree.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the TLR5 Gene Legionnaire Disease Susceptibility to Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Family history of Legionnaire disease
  • ✓Recurrent pneumonia or severe respiratory illness
  • ✓Individuals with underlying cardiovascular conditions
  • ✓Assessment of genetic risk for Legionnaire disease
  • ✓Patients with unexplained respiratory symptoms
02

In plain language

What this test helps you understand

Identifies genetic variations in the TLR5 gene associated with susceptibility to Legionnaire disease. Provides information to guide risk assessment and preventive health strategies.
The TLR5 Gene Legionnaire Disease Susceptibility test is a genetic analysis designed to identify potential predisposition to Legionnaire disease, a serious respiratory infection caused by Legionella bacteria. This test examines specific variations within the TLR5 gene, which plays a role in the body's immune response to this bacterium. Understanding your genetic makeup related to TLR5 can provide valuable insights for healthcare providers in assessing risk and guiding preventive strategies. This test is particularly relevant for individuals with a family history of Legionnaire disease or related respiratory conditions, or those experiencing symptoms suggestive of the illness. Results can help inform health management decisions and potential lifestyle adjustments.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationA detailed clinical history of the patient is required. A genetic counselling session is recommended prior to testing to discuss the test's purpose, limitations, and potential implications, including creating a family pedigree.
SampleBlood sample (EDTA tube), extracted DNA, or dried blood spot on an FTA card.
MethodologyNext-Generation Sequencing (NGS) analysis of the TLR5 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test identifies specific genetic variations associated with susceptibility, but does not guarantee the development of Legionnaire disease. Other genetic and environmental factors also play a role. Results should be interpreted by a qualified healthcare professional.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Legionnaire disease is a severe form of pneumonia caused by Legionella bacteria, often found in water systems. It can cause serious respiratory illness.
This test is recommended for individuals with a family history of Legionnaire disease, those with recurrent pneumonia, or people with specific underlying health conditions.
The TLR5 gene provides instructions for making a protein that helps the immune system recognise and respond to certain bacteria, including Legionella.
No, this test identifies genetic factors that may increase susceptibility. It does not predict with certainty whether you will develop the disease.
Results indicate the presence or absence of specific genetic variations. A healthcare provider or genetic counsellor should interpret the results in the context of your overall health.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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