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Medical information Clinical review pending

Genetic Testing

TMEM127 Gene Pheochromocytoma Type 8 Genetic Test

Genetic test to identify mutations in the TMEM127 gene, associated with an increased risk of developing pheochromocytoma, a rare adrenal gland tumor.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (typically collected in an EDTA tube). Confirm specific requirements with the laboratory before booking.
Results
Confirm turnaround time with the laboratory before booking.
Preparation
No special preparation is typically required for this blood test. However, confirm with the laboratory for any specific instructions.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the TMEM127 Gene Pheochromocytoma Type 8 Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Family history of pheochromocytoma or related endocrine tumors.
  • ✓Symptoms suggestive of pheochromocytoma (e.g., hypertension, palpitations, sweating).
  • ✓Personal history of pheochromocytoma.
  • ✓Screening for hereditary syndromes associated with pheochromocytoma.
  • ✓Genetic counseling for individuals concerned about hereditary cancer risk.
02

In plain language

What this test helps you understand

This test helps identify individuals with mutations in the TMEM127 gene, which are associated with an increased risk of developing pheochromocytoma. Identifying these mutations can guide clinical management, surveillance strategies, and family screening.
The TMEM127 Gene Pheochromocytoma Type 8 NGS Genetic DNA Test is a diagnostic tool used to identify genetic mutations linked to pheochromocytoma. This rare tumor affects hormone production in the adrenal glands. The test uses Next-Generation Sequencing (NGS) technology for accurate analysis of the TMEM127 gene, which is involved in the development of this condition. Detecting mutations in this gene helps healthcare providers assess risk and plan appropriate monitoring and management strategies. This test is particularly relevant for individuals with a family history of pheochromocytoma or related endocrine tumors, those experiencing symptoms like high blood pressure, palpitations, or excessive sweating, or individuals with known genetic predispositions to cancer.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is typically required for this blood test. However, confirm with the laboratory for any specific instructions.
SampleBlood sample (typically collected in an EDTA tube). Confirm specific requirements with the laboratory before booking.
MethodologyNext-Generation Sequencing (NGS) is used to analyze the TMEM127 gene for specific mutations.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test analyzes only the TMEM127 gene. Pheochromocytoma can be caused by mutations in other genes. A negative result does not completely rule out the condition or other genetic risks. Results should be interpreted in conjunction with clinical findings and family history.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Pheochromocytoma is a rare tumor that usually develops in the adrenal glands, affecting hormone production and potentially causing symptoms like high blood pressure, sweating, and palpitations.
Mutations in the TMEM127 gene are known to increase the risk of developing pheochromocytoma. Testing helps identify individuals who may carry this genetic predisposition.
Individuals with a family history of pheochromocytoma, those experiencing related symptoms, or those with a personal history of the condition should discuss this test with their doctor.
Your results will be interpreted by a healthcare professional, often a genetic counselor, who will explain the findings and discuss potential implications for your health and family.
Insurance coverage varies. Confirm coverage details with your insurance provider and the laboratory before booking.
A blood sample is typically required for this test. The laboratory can provide details on collection methods, including potential home collection services.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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