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Medical information Clinical review pending

Genetic Testing

TPI1 Gene Hemolytic Anemia Due to Triosephosphate Isomerase Deficiency Genetic Test

Genetic test to identify mutations in the TPI1 gene, which can cause hemolytic anemia. This test uses Next Generation Sequencing (NGS) technology to analyze DNA.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card. Confirm specific requirements with the laboratory before booking.
Results
Confirm with the laboratory before booking.
Preparation
No specific patient preparation is required. A clinical history and genetic counseling session is recommended prior to testing.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the TPI1 Gene Hemolytic Anemia Due to Triosephosphate Isomerase Deficiency Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Individuals with symptoms suggestive of hemolytic anemia (e.g., fatigue, pallor, jaundice).
  • ✓Family history of hemolytic anemia.
  • ✓Confirmation of suspected triosephosphate isomerase deficiency.
  • ✓Genetic counseling for individuals or families with a history of the condition.
  • ✓Prenatal diagnosis in families with a known TPI1 mutation.
02

In plain language

What this test helps you understand

This test helps identify individuals with mutations in the TPI1 gene, confirming a diagnosis of triosephosphate isomerase deficiency, a cause of chronic hemolytic anemia. It can aid in genetic counseling and family planning.
The TPI1 Gene Hemolytic Anemia Test is a genetic examination designed to detect triosephosphate isomerase deficiency, a rare inherited condition affecting red blood cell production. This deficiency can lead to chronic hemolytic anemia, where red blood cells are destroyed faster than they can be made. Understanding your genetic status regarding the TPI1 gene is important for managing potential health issues. This test utilizes Next Generation Sequencing (NGS) technology to identify specific mutations within the TPI1 gene. It provides a detailed analysis of your genetic information related to this condition, aiding in early diagnosis and appropriate management strategies. Consulting with a healthcare professional is recommended to discuss the test and its implications.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo specific patient preparation is required. A clinical history and genetic counseling session is recommended prior to testing.
SampleBlood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card. Confirm specific requirements with the laboratory before booking.
MethodologyNext Generation Sequencing (NGS) of the TPI1 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test detects mutations within the TPI1 gene. It may not detect all possible mutations. Results should be interpreted by a qualified healthcare professional. This test does not rule out other causes of hemolytic anemia.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

It is a rare inherited metabolic disorder affecting red blood cells, caused by mutations in the TPI1 gene. It can lead to chronic hemolytic anemia.
Individuals with symptoms of hemolytic anemia, a family history of the condition, or those seeking confirmation of a suspected diagnosis should consider this test.
The test analyzes a sample of your blood or DNA using Next Generation Sequencing (NGS) to look for mutations in the TPI1 gene.
Results will indicate the presence or absence of specific TPI1 gene mutations. A healthcare professional or genetic counselor should interpret the results in the context of your medical history.
Yes, genetic counseling before and after testing is highly recommended to understand the implications of the results and discuss family planning options.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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