Skip to main content
●+254 119 023975 support@dnalabskenya.com
Patient Portal LoginB2B / Doctor Portal
DNA LabsKenya
Medical information Clinical review pending

Genetic Testing

UNC13D Gene Hemophagocytic Lymphohistiocytosis Type 3 Genetic Test

Genetic test for UNC13D gene mutations associated with Hemophagocytic Lymphohistiocytosis (HLH) Type 3, using Next-Generation Sequencing (NGS). Helps identify genetic predispositions for timely diagnosis and management.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

Ask a question
Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube), Extracted DNA, or One drop of blood on an FTA card.
Results
Approximately 3 to 4 weeks. Confirm with the laboratory before booking.
Preparation
A clinical history assessment is required before the test. Genetic counseling is recommended, including drawing a family pedigree chart.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the UNC13D Gene Hemophagocytic Lymphohistiocytosis Type 3 Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

+254

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

WhatsApp the claims team Call us
01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Suspected Hemophagocytic Lymphohistiocytosis (HLH) Type 3
  • ✓Family history of HLH or related immune disorders
  • ✓Symptoms including prolonged fever, enlarged spleen, low blood cell counts
  • ✓Evaluation of genetic predisposition to immune system disorders
  • ✓Confirmation of diagnosis in individuals with clinical features of HLH
02

In plain language

What this test helps you understand

This test helps identify specific genetic mutations in the UNC13D gene associated with Hemophagocytic Lymphohistiocytosis (HLH) Type 3. It aids in confirming a diagnosis, understanding the genetic basis of the condition, and guiding treatment decisions. Results can also inform genetic counseling for families.
This test identifies genetic mutations in the UNC13D gene, which are linked to Hemophagocytic Lymphohistiocytosis (HLH) Type 3. HLH is a serious condition where the immune system becomes overactive, causing severe inflammation. This test uses advanced Next-Generation Sequencing (NGS) technology to analyze the UNC13D gene from a DNA sample. Early detection of these mutations is crucial for understanding the cause of the condition and guiding appropriate medical care. This test is particularly relevant for individuals with symptoms suggestive of HLH or a family history of the disorder. Discussing the results with a healthcare provider is essential for understanding the implications and planning next steps.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationA clinical history assessment is required before the test. Genetic counseling is recommended, including drawing a family pedigree chart.
SampleBlood sample (EDTA tube), Extracted DNA, or One drop of blood on an FTA card.
MethodologyNext-Generation Sequencing (NGS) of the UNC13D gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test specifically analyzes the UNC13D gene. It does not detect mutations in other genes associated with HLH or other conditions. Results must be interpreted by a qualified healthcare professional in conjunction with clinical findings. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

HLH is a rare and serious condition where the immune system becomes overactive, leading to severe inflammation and potential damage to organs.
The UNC13D gene provides instructions for making a protein important for the proper function of immune cells. Mutations in this gene can lead to HLH Type 3.
Individuals with symptoms suggestive of HLH, a family history of HLH or related immune disorders, or those recommended by their doctor should consider this test.
The test analyzes DNA extracted from a blood sample, extracted DNA, or a blood spot on an FTA card using Next-Generation Sequencing (NGS) technology.
The turnaround time is approximately 3 to 4 weeks. Confirm with the laboratory before booking.
It is essential to discuss the results with your doctor or a genetic counselor. They can explain the findings and discuss potential implications for your health and family.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

Keep exploring

Related tests

View all tests →

Beta CTx Beta Crosslaps Collagen Type 1 C-Telopeptide Test

The Beta CTx test measures bone resorption markers to help assess bone health and osteoporosis risk.

Learn more →

Bcell Rearrangement Detection Test

The Bcell Rearrangement Detection Test helps diagnose leukemia by identifying genetic changes in B cells. It's a key tool for hematologists and oncologists.

Learn more →

Dpd Gene Mutations 5Fu Toxicity Detection Test

This genetic test identifies mutations in the DPD gene, helping predict the risk of severe side effects from the chemotherapy drug 5-fluorouracil (5FU).

Learn more →

Ganciclovir Resistance Detection Test

This test checks for genetic changes in the cytomegalovirus (CMV) that may make it resistant to the antiviral medication Ganciclovir. It helps guide treatment decisions, especially for patients with weakened immune systems.

Learn more →
Chat on WhatsApp