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Medical information Clinical review pending

Genetic Testing

UNC45B Gene Cataract Type 43 Genetic Test

This genetic test identifies mutations in the UNC45B gene linked to cataract development. It's recommended for individuals with a family history of cataracts or early onset symptoms.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube) or Saliva sample (collection kit provided). Confirm with the laboratory before booking.
Results
Confirm with the laboratory before booking.
Preparation
No special preparation is required for a blood or saliva sample. Confirm with the laboratory before booking.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the UNC45B Gene Cataract Type 43 Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Individuals with a family history of cataracts.
  • ✓People experiencing early onset cataract symptoms.
  • ✓Patients referred by an ophthalmologist for genetic evaluation.
  • ✓Those seeking to understand their genetic predisposition to cataracts.
02

In plain language

What this test helps you understand

Identifies genetic mutations in the UNC45B gene associated with cataract development, aiding in risk assessment and proactive eye health management.
The UNC45B Gene Cataract Type 43 NGS Genetic DNA Test is a diagnostic tool used to identify genetic mutations associated with cataract formation. Cataracts are a common cause of vision impairment, and understanding your genetic risk can help with proactive eye health management. This test uses Next Generation Sequencing (NGS) technology for accurate results.

This test specifically looks for changes in the UNC45B gene, which are known to be linked to the development of cataracts. By analysing your genetic material, the test can help identify if you have an increased risk of developing cataracts, potentially allowing for early monitoring and management.

Understanding your results is important. A genetic counselor can help you interpret the findings and discuss what they mean for your eye health and future care.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is required for a blood or saliva sample. Confirm with the laboratory before booking.
SampleBlood sample (EDTA tube) or Saliva sample (collection kit provided). Confirm with the laboratory before booking.
MethodologyNext Generation Sequencing (NGS) of the UNC45B gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test only detects mutations within the UNC45B gene. Other genes can also cause cataracts. A negative result does not completely rule out a genetic predisposition. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

A cataract is a clouding of the lens in the eye, which can lead to vision loss. It is a common condition, especially in older adults.
This test specifically looks for genetic mutations in the UNC45B gene that are known to be associated with the development of cataracts.
This test is recommended for individuals with a family history of cataracts, those experiencing early onset cataracts, or those advised by an eye specialist.
Results are interpreted by genetic experts. A genetic counselor can help explain the findings and their implications for your eye health.
A blood sample or a saliva sample is required for this test. The laboratory can provide collection kits if needed.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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