Medical information Clinical review pending

Genetic Testing

WNK4 Gene Pseudohypoaldosteronism Type 2B Genetic Test

Genetic test using Next-Generation Sequencing (NGS) to identify mutations in the WNK4 gene associated with Pseudohypoaldosteronism Type 2B, a condition affecting kidney function and electrolyte balance.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

Ask a question

Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (EDTA tube) or extracted DNA. A drop of blood on an FTA card may also be acceptable. Confirm specific requirements with the laboratory before booking.
Results: Confirm with the laboratory before booking.
Preparation: No specific patient preparation is required for the blood draw. However, a genetic counseling session is recommended prior to testing to discuss the implications and family history.

Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the WNK4 Gene Pseudohypoaldosteronism Type 2B Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

Full name *

Mobile number *

+254

Insurer or scheme

Policy / member number (optional)

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

WhatsApp the claims team Call us

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Individuals with symptoms of high blood pressure.
✓Individuals with low potassium levels (hypokalemia).
✓Individuals with a family history of kidney or endocrine disorders.
✓Individuals with a clinical suspicion of Pseudohypoaldosteronism Type 2B.
✓Genetic counseling for families with affected members.

In plain language

What this test helps you understand

Identifies mutations in the WNK4 gene associated with Pseudohypoaldosteronism Type 2B, aiding in the diagnosis of this specific genetic condition affecting kidney function and electrolyte balance.

The WNK4 Gene Pseudohypoaldosteronism Type 2B NGS Genetic DNA Test is a diagnostic tool using Next-Generation Sequencing (NGS) technology. It identifies mutations in the WNK4 gene, which are linked to Pseudohypoaldosteronism Type 2B. This condition impacts kidney function and the body's regulation of electrolytes like sodium and potassium. Understanding the genetic basis of this condition is vital for proper management and treatment. This test analyzes your genetic code to detect specific variations in the WNK4 gene that may cause or contribute to the disorder. It is recommended for individuals showing symptoms like high blood pressure or low potassium levels, or those with a family history of kidney or endocrine disorders. Taking this test can lead to an accurate diagnosis, inform treatment decisions, help understand hereditary risks for family members, and guide lifestyle adjustments. Results will be provided in a detailed report, which should be discussed with a healthcare provider for interpretation and guidance on next steps. Sample collection involves a blood draw or extracted DNA. Genetic counseling is recommended before testing.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationNo specific patient preparation is required for the blood draw. However, a genetic counseling session is recommended prior to testing to discuss the implications and family history.

SampleBlood sample (EDTA tube) or extracted DNA. A drop of blood on an FTA card may also be acceptable. Confirm specific requirements with the laboratory before booking.

MethodologyNext-Generation Sequencing (NGS) targeting the WNK4 gene.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

This test specifically analyzes the WNK4 gene. It may not detect mutations in other genes that could cause similar symptoms. A negative result does not completely rule out a genetic cause for the condition. Interpretation requires clinical correlation.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

Pseudohypoaldosteronism Type 2B is a genetic disorder affecting the kidneys' ability to regulate sodium and potassium levels, often leading to high blood pressure and low potassium.

Genetic counseling helps you understand the test, its implications, potential results, and how it might affect you and your family. It also helps in collecting relevant family history.

Typically, a blood sample is required. In some cases, extracted DNA or a blood spot on an FTA card may be used. Please confirm the exact requirement with the lab.

Turnaround time varies. Please contact the laboratory directly for the current estimated timeframe.

It is essential to discuss your results with your doctor or a genetic counselor. They can help interpret the findings and discuss potential next steps, including treatment or family planning.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

Keep exploring

Related tests

View all tests →

Chat on WhatsApp