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Genetic Testing

ZAP70 Gene Selective Tcell Defect Genetic Test

The ZAP70 Gene Selective Tcell Defect NGS Genetic DNA Test identifies mutations in the ZAP70 gene, crucial for T-cell function and immune response. This test helps diagnose specific immunodeficiencies.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood sample (EDTA tube). Confirm with the laboratory before booking.
Results
Confirm with the laboratory before booking.
Preparation
No special preparation is required for this test. Confirm with the laboratory before booking.
Test priceKSh 40,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the ZAP70 Gene Selective Tcell Defect Genetic Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Recurrent or severe infections
  • ✓Suspected primary immunodeficiency
  • ✓Family history of T-cell deficiency
  • ✓Diagnosis of specific T-cell defects
  • ✓Evaluation of autoimmune conditions
02

In plain language

What this test helps you understand

This test helps identify specific genetic mutations in the ZAP70 gene associated with T-cell immunodeficiency, aiding in diagnosis and guiding management strategies for immune disorders.
The ZAP70 Gene Selective Tcell Defect NGS Genetic DNA Test is a specialized diagnostic tool designed to identify genetic mutations in the ZAP70 gene. This gene plays a critical role in T-cell signaling and the body's immune response. The test utilizes Next-Generation Sequencing (NGS) technology to provide detailed insights into genetic disorders that can lead to severe immunological issues. Understanding your genetic makeup is vital for diagnosing and managing various immunological disorders. The ZAP70 gene is essential for the proper functioning of T-cells, which are crucial for an effective immune response. This test is particularly important for individuals with unexplained recurrent infections or immunodeficiencies. This test specifically detects mutations in the ZAP70 gene that can lead to T-cell defects. By analyzing the genetic material, healthcare providers can ascertain the presence of these mutations and their potential impact on immune function. Upon receiving your test results, your healthcare provider will explain the findings and their implications. Results will indicate whether any mutations in the ZAP70 gene were detected and what that means for your health. It is essential to discuss these results in the context of your clinical history and symptoms.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo special preparation is required for this test. Confirm with the laboratory before booking.
SampleBlood sample (EDTA tube). Confirm with the laboratory before booking.
MethodologyNext-Generation Sequencing (NGS) of the ZAP70 gene.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test detects mutations within the ZAP70 gene. It does not detect mutations in other genes associated with immunodeficiency. Results may be affected by sample quality. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

The ZAP70 gene provides instructions for making a protein that is important for the development and function of T-cells, a type of white blood cell crucial for the immune system.
This test helps identify specific genetic mutations that can cause T-cell defects, leading to immunodeficiency. Early diagnosis can guide appropriate treatment and management.
Individuals with recurrent infections, a history of severe immune problems, or a family history of T-cell deficiencies may be recommended for this test.
The test involves analyzing a blood sample to look for specific changes (mutations) in the ZAP70 gene using Next-Generation Sequencing (NGS) technology.
A healthcare provider will interpret the results in the context of your medical history and symptoms to determine the significance of any detected mutations.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

Explore partnerships
09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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