Medical information Clinical review pending

Gynecological Testing

HE4 Human Epididymis Protein 4 Test

The HE4 Human Epididymis Protein 4 Test measures levels of the HE4 protein in the blood, aiding in the detection and monitoring of certain cancers, particularly ovarian cancer. This test is a valuable tool for early diagnosis and treatment planning.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample: Blood sample (Serum or Plasma). Confirm specific requirements with the laboratory before booking.
Results: Results are typically available on the same day. Confirm exact turnaround time with the laboratory before booking.
Preparation: No special preparation is typically required. However, confirm with the laboratory regarding fasting or medication restrictions before booking.

Test priceKSh 7,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the HE4 Human Epididymis Protein 4 Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

Insurer or scheme name & policy / member number
A clinician's request / prescription for the test
Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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+254

Insurer or scheme

Policy / member number (optional)

Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

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Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

✓Evaluation of women with symptoms suggestive of ovarian cancer (e.g., abdominal bloating, pain).
✓Risk assessment in women with a family history of ovarian or breast cancer.
✓Monitoring for recurrence in patients previously diagnosed with ovarian cancer.
✓Assisting in the differentiation of benign from malignant pelvic masses.
✓Evaluating patients with elevated CA125 levels.

In plain language

What this test helps you understand

The HE4 test aids in the assessment of risk for ovarian cancer, particularly in conjunction with other markers like CA125, and can assist in monitoring patients diagnosed with ovarian cancer.

The HE4 Human Epididymis Protein 4 Test is a diagnostic tool used primarily in gynecological oncology. It measures the level of the HE4 protein in a blood sample. Elevated levels can be an indicator of certain cancers, especially ovarian cancer. Early detection is key for successful treatment, making this test important for cancer screening. The test quantifies the HE4 protein produced by reproductive tract cells. Monitoring these levels helps healthcare providers assess cancer risk and guide decisions about further tests or treatment. This test is often recommended for women experiencing symptoms like abdominal pain or bloating, those with a family history of ovarian or breast cancer, or patients monitoring for cancer recurrence. Taking the HE4 test can lead to early detection, assist in monitoring cancer progression, and provide information to guide treatment decisions. Results are typically available on the same day and should be discussed with a healthcare provider for interpretation and next steps. We offer testing at branches across major cities in Kenya and provide home sample collection services. Confirm with the laboratory before booking.

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

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A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

Speak with us

We check the test and answer your questions before collection.

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

Understand your report

A counselor helps you understand the result and the next steps.

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →

PreparationNo special preparation is typically required. However, confirm with the laboratory regarding fasting or medication restrictions before booking.

SampleBlood sample (Serum or Plasma). Confirm specific requirements with the laboratory before booking.

MethodologyImmunoassay (e.g., ELISA or Chemiluminescence). Confirm specific methodology with the laboratory before booking.

PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.

The HE4 test is not a standalone diagnostic tool. Elevated levels can be associated with other conditions besides cancer. False negatives and false positives can occur. Results must be interpreted by a qualified healthcare professional in conjunction with other clinical information.

Read your report

What common result terms mean

TermPlain-language meaning

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.

NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.

VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.

Questions people ask

Frequently asked questions

The HE4 test measures the level of the Human Epididymis Protein 4 in your blood, which can be elevated in certain types of cancer, particularly ovarian cancer.

This test may be recommended for women with symptoms suggestive of ovarian cancer, those with a family history of ovarian or breast cancer, or patients monitoring for cancer recurrence. Discuss with your doctor.

No, the HE4 test is not a standalone diagnostic test. It helps assess risk and monitor disease but must be interpreted alongside other clinical findings and tests by a healthcare professional.

Results are typically available on the same day. Confirm the exact turnaround time with the laboratory.

Insurance coverage varies. Please check with your insurance provider regarding coverage for the HE4 test.

We offer testing at branches across major cities in Kenya and provide home sample collection services. Contact us to book.

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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Trust & transparency

Sources, standards & how this page is maintained

Standards & references

ACMG/AMP technical standards for sequence variant interpretation
ClinGen curation and gene–disease validity frameworks where applicable
LOINC-coded reporting for interoperable results
ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

Last updated: September 27, 2026
Medical review: not yet completed
Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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