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Medical information Clinical review pending

Immunology Testing

Systemic Sclerosis Profile IgG Test

The Systemic Sclerosis Profile IgG Test helps detect specific antibodies associated with systemic sclerosis (scleroderma), an autoimmune disorder. This test aids in diagnosis and guides treatment.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
2 mL (1 mL minimum) serum collected in an SST tube.
Results
Results are typically available the same day by 6 pm, provided the sample is collected by 11 am Monday to Saturday. Confirm with the laboratory before booking.
Preparation
Confirm with the laboratory before booking. Generally, no special preparation is required, but fasting may be requested. Follow any specific instructions provided by your doctor or the laboratory.
Test priceKSh 33,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Systemic Sclerosis Profile IgG Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Symptoms suggestive of systemic sclerosis (e.g., skin thickening, Raynaud's phenomenon).
  • ✓Evaluation of autoimmune disorders.
  • ✓Family history of autoimmune diseases.
  • ✓Monitoring disease progression in diagnosed patients.
  • ✓Assisting in differential diagnosis of connective tissue diseases.
02

In plain language

What this test helps you understand

This test aids in the diagnosis of systemic sclerosis (scleroderma) and related autoimmune conditions by detecting specific autoantibodies. It helps clinicians assess risk, guide treatment strategies, and monitor disease activity.
The Systemic Sclerosis Profile IgG Test is a diagnostic tool used to identify autoimmune disorders, particularly systemic sclerosis (scleroderma). This condition can affect the skin, blood vessels, and internal organs. The test detects specific antibodies that indicate the presence of this complex condition.

This test measures various antibodies associated with systemic sclerosis, including Scl-70, CENP A, CENP B, RP11, RP155, Fibrillarin, NOR90, Th/To, PM-Scl 100, PM-Scl 75, Ku, PDGFR, and Ro-52.

This test is recommended for individuals experiencing symptoms suggestive of autoimmune disorders, such as skin thickening or tightening, Raynaud's phenomenon, joint pain or swelling, fatigue, digestive issues, or shortness of breath. Individuals with a family history of autoimmune diseases may also benefit from this test.

Understanding your autoimmune status through this test can facilitate early diagnosis and management of systemic sclerosis, guide treatment decisions, and monitor disease progression.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationConfirm with the laboratory before booking. Generally, no special preparation is required, but fasting may be requested. Follow any specific instructions provided by your doctor or the laboratory.
Sample2 mL (1 mL minimum) serum collected in an SST tube.
MethodologyImmunoassay (e.g., ELISA or Immunofluorescence). Confirm with the laboratory before booking.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test detects specific antibodies associated with systemic sclerosis but does not confirm the diagnosis alone. Clinical evaluation and other tests are necessary. A negative result does not completely rule out the condition. Confirm with the laboratory before booking.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Systemic sclerosis, also known as scleroderma, is a chronic autoimmune disease where the immune system attacks the body's connective tissues, leading to hardening and tightening of the skin and potential damage to internal organs.
This test helps identify specific antibodies linked to systemic sclerosis, aiding in early diagnosis, guiding treatment decisions, and monitoring the condition's progression.
Symptoms like skin thickening, Raynaud's phenomenon (color changes in fingers/toes in cold), joint pain, fatigue, and digestive problems may indicate the need for this test.
A blood sample is required for this test. A healthcare professional will draw blood, typically from a vein in your arm.
Results are usually available the same day by 6 pm if the sample is collected by 11 am from Monday to Saturday. Confirm with the laboratory before booking.
Confirm with the laboratory before booking. While not always required, fasting might be recommended in some cases.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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