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Medical information Clinical review pending

Metabolic Testing

Osmolal Gap Serum Test

The Osmolal Gap Serum Test measures serum osmolality to help identify unmeasured solutes, aiding in the diagnosis of metabolic disorders. Available across Kenya with same-day reporting.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
3 mL of serum from an SST tube and 2 mL of plasma from a Grey Top (Sodium Fluoride) tube.
Results
Reports are typically available on the same day if samples are collected by 4 PM.
Preparation
Confirm with the laboratory before booking. No specific patient preparation is typically required, but inform your doctor about any medications or supplements you are taking.
Test priceKSh 2,293

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Osmolal Gap Serum Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Unexplained confusion
  • ✓Severe dehydration
  • ✓Changes in consciousness
  • ✓Electrolyte imbalances
  • ✓Suspected toxic alcohol ingestion
  • ✓Evaluation of kidney function
  • ✓Monitoring metabolic disorders
02

In plain language

What this test helps you understand

The Osmolal Gap Serum Test helps identify the presence of unmeasured solutes in the serum, which can indicate various health conditions, including toxic alcohol ingestion, kidney failure, and certain metabolic disorders. It aids in the diagnosis and management of electrolyte imbalances and metabolic disturbances.
The Osmolal Gap Serum Test is a diagnostic tool used to assess metabolic disorders. It measures the osmolality of serum, reflecting the concentration of solutes in the blood. This test is important for identifying the presence of unmeasured solutes, which can indicate various health conditions.

This test measures the osmolality of serum and detects levels of key components such as sodium, BUN (Blood Urea Nitrogen), and glucose.

This test is recommended for individuals experiencing symptoms related to metabolic disorders, such as unexplained confusion, severe dehydration, changes in consciousness, or electrolyte imbalances. Those with risk factors like diabetes, kidney disease, or substance abuse may also benefit from this test.

Taking this test helps diagnose serious metabolic disorders, provides insights into electrolyte imbalances, and enables timely medical intervention. Same-day reporting allows for rapid decision-making.

Interpreting the results requires a healthcare professional. A higher osmolal gap may indicate unmeasured solutes like alcohols or toxins. Your healthcare provider will discuss your results and recommend further action if needed.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationConfirm with the laboratory before booking. No specific patient preparation is typically required, but inform your doctor about any medications or supplements you are taking.
Sample3 mL of serum from an SST tube and 2 mL of plasma from a Grey Top (Sodium Fluoride) tube.
MethodologyCalculated based on measured serum sodium, BUN, and glucose levels compared to measured serum osmolality.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
Grossly hemolysed samples are not accepted. Results can be affected by certain medications or conditions. This test is not a standalone diagnostic tool and should be interpreted in conjunction with clinical findings and other laboratory results.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

Serum osmolality measures the concentration of dissolved particles in your blood serum. It helps assess your body's fluid balance and kidney function.
The osmolal gap is the difference between the measured osmolality and the calculated osmolality based on electrolytes and glucose. An increased gap can suggest the presence of unmeasured substances like alcohols or toxins.
Symptoms like unexplained confusion, severe dehydration, changes in consciousness, or electrolyte imbalances may prompt your doctor to order this test.
Results are typically available on the same day if the sample is collected by 4 PM. Confirm with the laboratory for specific turnaround times.
Confirm with the laboratory before booking. Generally, fasting is not required, but it's best to check with your doctor or the lab.
Yes, home sample collection services are available. Please contact us to arrange for collection.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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