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Medical information Clinical review pending

Neurology

Anti-NMO Neuromyelitis Optica Antibody Aquaporin 4 Test

The Anti-NMO Neuromyelitis Optica Antibody Aquaporin 4 Test helps diagnose neuromyelitis optica (NMO), a serious autoimmune disorder affecting the nervous system. It detects antibodies against aquaporin-4, aiding in early diagnosis and treatment.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
2 mL (1 mL minimum) serum collected in an SST tube OR 1 mL (0.5 mL minimum) cerebrospinal fluid (CSF) collected in a sterile screw-capped container.
Results
Confirm with the laboratory before booking.
Preparation
No specific patient preparation is required for this test. Confirm with the laboratory before booking.
Test priceKSh 13,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the Anti-NMO Neuromyelitis Optica Antibody Aquaporin 4 Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Suspected Neuromyelitis Optica (NMO)
  • ✓Unexplained optic neuritis
  • ✓Unexplained transverse myelitis
  • ✓Symptoms suggestive of central nervous system autoimmune disease
  • ✓Differential diagnosis from Multiple Sclerosis
  • ✓Monitoring disease activity in diagnosed NMO patients
02

In plain language

What this test helps you understand

This test aids in the diagnosis of Neuromyelitis Optica Spectrum Disorder (NMOSD), differentiating it from other neurological conditions like Multiple Sclerosis. It helps identify patients who may benefit from specific treatments targeting the autoimmune process.
The Anti-NMO Neuromyelitis Optica Antibody Aquaporin 4 Test is a key diagnostic tool for identifying neuromyelitis optica (NMO), a severe autoimmune condition impacting the central nervous system. This test is important for early detection, as prompt diagnosis can help prevent significant neurological damage.

This test measures the presence of antibodies targeting aquaporin-4, a protein vital for central nervous system function. Detecting these antibodies is crucial for diagnosing NMO, indicating an autoimmune attack on the spinal cord and optic nerves.

Individuals experiencing symptoms like vision loss, limb weakness, coordination problems, temperature sensitivity, or bladder issues should discuss this test with their doctor, especially if there's a family history of autoimmune diseases or unexplained neurological events.

Benefits of this test include accurate NMO diagnosis, guidance for treatment planning to minimize further nerve damage, and clarity regarding symptoms. Results indicate whether aquaporin-4 antibodies are present. A positive result strongly suggests NMO, while a negative result may point towards other conditions. Discussing your results with a healthcare provider is essential for proper interpretation and next steps.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationNo specific patient preparation is required for this test. Confirm with the laboratory before booking.
Sample2 mL (1 mL minimum) serum collected in an SST tube OR 1 mL (0.5 mL minimum) cerebrospinal fluid (CSF) collected in a sterile screw-capped container.
MethodologyImmunofluorescence assay (IFA) or Enzyme-Linked Immunosorbent Assay (ELISA) to detect antibodies against aquaporin-4.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
A negative result does not completely rule out NMO, as some patients may test negative. Other autoimmune conditions can sometimes cause similar symptoms. Results must be interpreted in the context of clinical findings.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

NMO is a rare autoimmune disorder where the body's immune system attacks the optic nerves and spinal cord, leading to inflammation and damage.
Early diagnosis of NMO is crucial because prompt treatment can help prevent severe, permanent neurological damage, such as blindness or paralysis.
A positive result indicates the presence of antibodies against aquaporin-4, strongly suggesting NMO. A negative result means these specific antibodies were not detected, but further investigation may still be needed.
Symptoms like sudden vision loss in one or both eyes, weakness or paralysis in the limbs, numbness, tingling, loss of coordination, or bladder/bowel problems should prompt discussion with your doctor.
The test requires either a blood sample (serum) or a cerebrospinal fluid (CSF) sample, collected according to specific laboratory procedures.
Insurance coverage varies. Please check with your insurance provider regarding coverage for this specific test.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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