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Lynch Syndrome & Hereditary Colorectal Cancer

MLH1/MSH2/MSH6/PMS2 Mismatch Repair Panel

Catalog role labels reflect current assignments. Test choice, timing and prices require clinician or laboratory confirmation.

  • KMLTTB Regulated Laboratory
  • ISO 9001:2015 Quality System
  • Free Pre-Test Counselor Guidance
  • Nationwide & Home Sample Collection

Test comparison

33 tests

All diagnostic topics
First-line screen

Immunohistochemistry Microsatellite Instability Panel Test

Sample type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
Turnaround
5 Days Results are typically available within 5 days for blocks and tissue biopsies, and 7 days for large complex tissue samples.
Price
KSh 20,000
First-line screen

Microsatellite Instability MSI PCR Test

Sample type
Formalin-Fixed Paraffin-Embedded (FFPE) tissue block from the tumor.
Turnaround
Timing on request
Price
KSh 32,000
First-line screen

Oncopro 350 Gene TMB MSI Profile Test

Sample type
Formalin-fixed paraffin-embedded (FFPE) tissue block containing at least 10% tumor tissue.
Turnaround
Timing on request
Price
KSh 140,400
First-line screen

RHBDF2 Gene Tylosis with Esophageal Cancer Genetic Test

Sample type
Blood sample (EDTA tube) or extracted DNA.
Turnaround
4 Weeks Results are typically available within 3 to 4 weeks.
Price
KSh 40,000
First-line screen

Msh2 Gene Colorectal Cancer Hereditary Nonpolyposis Type 1 Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

MLH1 Gene Colorectal Cancer Hereditary Nonpolyposis Type 2 Genetic Test

Sample type
Blood sample (EDTA tube), extracted DNA, or FTA card with dried blood spot.
Turnaround
4 Weeks Approximately 3 to 4 weeks.
Price
KSh 40,000
First-line screen

PMS2 Gene Colorectal Cancer Hereditary Nonpolyposis Type 4 Genetic Test

Sample type
Blood sample (typically collected in an EDTA tube). Confirm specific requirements with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

Msh6 Gene Colorectal Cancer Hereditary Nonpolyposis Type 5 Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

TGFBR2 Gene Colorectal Cancer Hereditary Nonpolyposis Type 6 Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm specific requirements with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

MLH3 Gene Colorectal Cancer Hereditary Nonpolyposis Type 7 Genetic Test

Sample type
Blood sample (EDTA tube). Confirm with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

EPCAM Gene Colorectal Cancer Hereditary Nonpolyposis Type 8 Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

MC1R Gene Melanoma Cutaneous Malignant Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm specific requirements with the laboratory before booking.
Turnaround
4 Weeks Results are typically available within 3 to 4 weeks. Confirm exact turnaround time with the laboratory before booking.
Price
KSh 40,000
First-line screen

MITF Gene Melanoma Cutaneous Malignant Genetic Test

Sample type
Blood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
Turnaround
4 Weeks Approximately 3 to 4 weeks.
Price
KSh 40,000
First-line screen

CDKN2A Gene Melanoma Cutaneous Malignant Familial Genetic Test

Sample type
Blood sample, extracted DNA, or one drop of blood on an FTA card.
Turnaround
4 Weeks Approximately 3 to 4 weeks.
Price
KSh 40,000
First-line screen

POT1 Gene Melanoma Cutaneous Malignant Familial Type 10 Susceptibility to Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

XRCC3 Gene Melanoma Cutaneous Malignant Familial Type 6 Susceptibility to Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm specific requirements with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

CDK4 Gene Melanoma Cutaneous Malignant Familial CDK4 Related Genetic Test

Sample type
Blood sample or extracted DNA. Confirm specific requirements with the laboratory before booking.
Turnaround
4 Weeks Approximately 3 to 4 weeks.
Price
KSh 40,000
First-line screen

MLH1 Gene Mismatch Repair Cancer Syndrome Genetic Test

Sample type
Blood sample (usually collected in an EDTA tube). Confirm specific requirements with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

Msh2 Gene Mismatch Repair Cancer Syndrome Genetic Test

Sample type
Blood sample (EDTA tube), Extracted DNA, or One drop of blood on an FTA card.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

Msh6 Gene Mismatch Repair Cancer Syndrome Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm specific requirements with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

PMS2 Gene Mismatch Repair Cancer Syndrome Genetic Test

Sample type
Blood sample (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
Turnaround
4 Weeks Approximately 3 to 4 weeks.
Price
KSh 40,000
First-line screen

MMR Genes Gene MMR Genes Methylation Analysis Genetic Test

Sample type
Blood sample (EDTA tube), Extracted DNA, or One drop of blood on an FTA card.
Turnaround
4 Weeks Approximately 3 to 4 weeks.
Price
KSh 40,000
First-line screen

MLH1 Gene Muir-Torre Syndrome Genetic Test

Sample type
A blood sample is required for this test. Confirm with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

Msh2 Gene Muir-Torre Syndrome Genetic Test

Sample type
Blood sample (EDTA tube), Extracted DNA, or One drop of blood on an FTA card.
Turnaround
4 Weeks 3 to 4 weeks.
Price
KSh 40,000
First-line screen

RHBDF2 Gene Tylosis With Esophageal Cancer Genetic Test

Sample type
Blood sample (EDTA tube) or Saliva sample. Confirm specific requirements with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 40,000
First-line screen

Microsatellite Instability Lynch Syndrome Colorectal Cancer

Sample type
Tumor tissue sample (preferred) or peripheral blood sample. Confirm specific requirements with the laboratory before booking.
Turnaround
See timing details Confirm turnaround time with the laboratory before booking.
Price
KSh 30,000
First-line screen

Oncomine Comprehensive Panel, Oncomine Tumor Mutation Burden (TMB), MSI, PDL1

Sample type
Paraffin-embedded tumor tissue block and peripheral blood sample (EDTA Vacutainer tube, 3ml). Confirm specific requirements with the laboratory before booking.
Turnaround
2–3 Weeks Approximately 2-3 weeks. Confirm exact turnaround time with the laboratory before booking.
Price
KSh 240,000
First-line screen

Oncomine Comprehensive Panel Oncomine Tumor Mutation Burden MSI

Sample type
Tumor tissue sample and peripheral blood sample.
Turnaround
Timing on request
Price
KSh 210,000
First-line screen

Oncomine Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI)

Sample type
Paraffin-embedded tumor tissue block and peripheral blood collected in an EDTA Vacutainer tube (3 ml). Confirm with the laboratory before booking.
Turnaround
Timing on request
Price
KSh 105,000
First-line screen

Solid Tumor Combo2 MSI NRAS KRAS BRAF H RAS

Sample type
Formalin-fixed paraffin-embedded (FFPE) tumor tissue block or unstained slides. Confirm specific requirements with the laboratory before booking.
Turnaround
10 Days Results are typically available within 10 days. Confirm exact turnaround time with the laboratory before booking.
Price
KSh 72,000

Clinical context

Clinical testing guide & how to choose

Tests in Lynch Syndrome & Hereditary Colorectal Cancer answer different clinical questions. This catalogue supports a conversation with your clinician or counselor; it does not establish a diagnosis or replace an individual assessment.

Choosing a test

A comprehensive panel measures several related markers, while a single-marker test addresses a more focused question. A larger panel is not automatically the right choice. Discuss your symptoms, previous results and referral with a qualified clinician before selecting tests. Results should not be interpreted in isolation.

Before sample collection

Confirm the required tube, sample volume, any fasting instructions and the collection deadline for your chosen test. Tell the collection team about medication and recent treatment. Do not stop prescribed medication unless your clinician advises it. Home collection depends on the sample’s handling and transport requirements.

Common questions

Questions before booking

Should I choose a panel or a single-marker test for Lynch Syndrome & Hereditary Colorectal Cancer?

A comprehensive panel measures several related markers, while a single-marker test addresses a more focused question. A larger panel is not automatically the right choice. Discuss your symptoms, previous results and referral with a qualified clinician before selecting tests. Results should not be interpreted in isolation. Free pre-test counselor guidance is available to help you understand the booking options.

Can I use SHIF/SHA or private insurance for these tests?

Coverage depends on your scheme, the specific test, referral and authorization requirements, and the provider arrangement. Before booking, ask the laboratory and your insurer to verify eligibility, any co-payment, and whether direct billing or reimbursement applies. Listing a test here does not guarantee insurance coverage.

When should I arrange sample collection?

Check the sample and preparation notes for the specific test, then confirm the collection time and reporting deadline with the laboratory. Same-day reporting, where listed, may depend on a collection cutoff and working days. Nationwide and home sample collection are available subject to location, sample suitability and transport arrangements.

Quick factsheet

Sample
Preparation
Turnaround