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Transplant Testing

HLA DSA Donor Specific IgG Antibodies Class I II Test

The HLA DSA Donor Specific IgG Antibodies Class I II Test helps assess compatibility for organ transplantation by detecting antibodies that could affect the success of the transplant. This test is important for patients undergoing transplantation, especially those with risk factors.

General information only: This page is not a diagnosis or personal medical advice. A qualified clinician should decide whether testing is appropriate and interpret results in context.

Review status: No completed medical review is recorded for this page.

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Counselor guidance included Confidential handling Kenya-wide coordination

At a glance

Plan your test

Sample
Blood or serum.
Results
Approximately 10-12 days. Confirm with the laboratory before booking.
Preparation
Confirm with the laboratory before booking. Sample should preferably be collected 48 hours after dialysis. A doctor's prescription on letterhead with a stamp is required, along with one photograph each of the recipient and donor.
Test priceKSh 26,000

Payment: M-Pesa and card options can be confirmed during booking.

Insurance & government schemes

Is this test covered for you?

We help you verify whether the HLA DSA Donor Specific IgG Antibodies Class I II Test test can be claimed against your insurer, employer scheme or a Kenyan government health scheme — before you book. Coverage depends on your plan, clinical indication and your provider's rules; final approval always rests with them.

Talk to a claims advisor

Providers & schemes we can help you check

Government & public schemes

SHIF — Social Health Insurance Fund Linda Mama EduAfya NHIF (legacy cards)

Eligibility and benefits follow the current rules of the Social Health Authority (SHA) and applicable government programmes.

Private insurers & employer schemes

Jubilee Health AAR APA Britam CIC Madison Resolution Pioneer Minet Old Mutual GA Life Heritage + other licensed insurers

Names shown for identification only — listing does not imply partnership or guarantee of coverage.

Have these ready when we check

  • Insurer or scheme name & policy / member number
  • A clinician's request / prescription for the test
  • Pre-authorisation letter, if your plan requires one

Free coverage check

Ask us to verify your cover

Send your details and our claims team confirms what documents you need and whether pre-authorisation applies — usually the same working day.

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Used only to process your coverage check — see our Privacy Policy. Verification support is free and does not guarantee your provider will pay.

01

Start with fit

Is this the right test for you?

The best test starts with a clear clinical question. These are common reasons a clinician or family may consider this test.

  • ✓Patients undergoing organ transplantation.
  • ✓Patients with a history of previous transplants.
  • ✓Patients with known sensitization to HLA antigens.
  • ✓Monitoring post-transplant patients for rejection risk.
  • ✓Investigating unexplained organ dysfunction after transplant.
02

In plain language

What this test helps you understand

This test helps assess the risk of transplant rejection by identifying donor-specific antibodies (DSA) in the recipient's blood. It aids in monitoring patients post-transplant and guiding treatment decisions to improve graft survival.
The HLA DSA Donor Specific IgG Antibodies Class I II Test is a critical diagnostic tool used in organ transplantation. It helps identify donor-specific antibodies in the recipient's blood, which can impact the body's acceptance of a transplanted organ. Early detection is essential for managing potential rejection risks.

This test measures the presence of donor-specific IgG antibodies against Class I and Class II Human Leukocyte Antigens (HLA). Monitoring these antibodies is crucial for patients undergoing transplantation as their presence can indicate a heightened risk of transplant rejection.

Patients who have undergone previous transplants, those with a history of sensitization to HLA antigens, or individuals with certain medical conditions may be advised to take this test. It may also be considered if there is unexplained organ dysfunction after a transplant.

Taking this test offers several benefits, including early detection of potential transplant rejection risks, guidance for post-transplant care, and informed decision-making for patients and healthcare providers. Understanding your results is crucial for your healthcare journey. A positive result indicates the presence of donor-specific antibodies, which may require further evaluation and management by your transplant team. Regular monitoring may be necessary.

We have branches across major cities in Kenya and offer a home sample collection service. To book your test or for more information, please contact us.
03

Medical review status

Clinical review pending

A completed medical review is not recorded for this page. No clinician has endorsed the information shown here. Please discuss testing decisions with a qualified healthcare professional.

Meet the DNA Labs Kenya medical team →
04

A simple process

What happens next?

You do not have to navigate the test alone. We help you move from question to next step.

1

Speak with us

We check the test and answer your questions before collection.

2

Give your sample

Choose home collection or a coordinated hub visit in Kenya. We explain whether this test uses a cheek swab or blood draw.

3

Understand your report

A counselor helps you understand the result and the next steps.

05

Choose your collection

Home collection or a lab visit

We will explain the sample, preparation, and next steps before anything is collected.

Home collection

Choose a coordinated visit at home or another convenient location. Our team confirms the appointment and sample requirements in advance.

Lab or hub visit

Prefer to visit a coordinated location? We can guide you to the right hub and explain what to expect when you arrive.

Ask about locations →
PreparationConfirm with the laboratory before booking. Sample should preferably be collected 48 hours after dialysis. A doctor's prescription on letterhead with a stamp is required, along with one photograph each of the recipient and donor.
SampleBlood or serum.
MethodologyLuminex X-Map technology.
PrivacyYour sample and report are handled confidentially. Ask the team how your information is stored and shared.
This test detects IgG antibodies against HLA Class I and Class II antigens. It does not detect other types of antibodies or predict all forms of transplant rejection. Results should be interpreted in the clinical context by a qualified healthcare professional.
06

Read your report

What common result terms mean

PositiveA finding was identified. Your clinician or counselor will explain what it means for your care.
NegativeThe specific finding tested for was not identified. It does not rule out every possible cause.
VUSA variant was found, but current evidence is not enough to classify it. Your counselor can explain follow-up.
07

Questions people ask

Frequently asked questions

HLA DSA stands for Human Leukocyte Antigen Donor Specific Antibody. These are antibodies in a recipient's blood that target specific HLA antigens on a donor organ, potentially leading to transplant rejection.
This test helps identify the presence of DSA, which can indicate a higher risk of the body rejecting the transplanted organ. Early detection allows doctors to manage this risk proactively.
This test is typically recommended for patients before or after organ transplantation, especially those with a history of previous transplants, blood transfusions, or sensitization.
A positive result means donor-specific antibodies were detected. Your transplant team will interpret this result in the context of your overall health and transplant history to determine the appropriate management plan.
The sample is typically collected as blood or serum. Specific instructions regarding timing, such as collection after dialysis, may apply. Please check with the lab for details.
08

Collaboration

Open for partnership with hospitals, clinics, doctors & researchers

Whether you are referring patients, building a research programme or supporting students, we work as an extension of your team — with responsive communication and clear scientific standards.

Hospitals & clinics

Referral pathways, coordinated sample logistics and shared reporting that fits your clinical workflow.

Doctors & specialists

LOINC-coded reports, ACMG-based variant classification and a direct scientific line for complex cases.

Research institutions

Sanger sequencing, NGS panels and custom assays — with project design support, batch pricing and agreed turnaround commitments.

Students & academic projects

Discounted laboratory services for college, master's and PhD research projects — including proposal guidance and cost-effective batch testing.

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09

Trust & transparency

Sources, standards & how this page is maintained

Standards & references

  • ACMG/AMP technical standards for sequence variant interpretation
  • ClinGen curation and gene–disease validity frameworks where applicable
  • LOINC-coded reporting for interoperable results
  • ISO 9001:2015 quality management; ISO 15189 accreditation in progress

Page provenance

  • Last updated: September 27, 2026
  • Medical review: not yet completed
  • Written for patients & clinicians in Kenya; reviewed periodically against current guidance

Medical disclaimer: this page is general information, not a diagnosis or personal medical advice. Testing decisions and result interpretation should be made with a qualified healthcare professional.

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